Prevalence and associated factors of the use of opioids in the treatment of chronic non-cancer pain. Perspective of the general Spanish population and the experience of patients.
type: CreativeWork
description: Aims The general aim of this thesis was to study the situation of opioid treatments for chronic noncancer pain (CNCP). The specific aims were: first, to determine and synthesize the prevalence of the therapeutic use of opioids in patients with CNCP, and to analyze the factors associated with their use through a systematic review of the literature and a meta-analysis; second, to investigate the evolution of opioid-related mortality and potential years of life lost in the general population in Spain from 2008 to 2017 and to compare the results by gender and age with the United States; third, to describe the current perspective of the Spanish population toward opioid use in the treatment of pain and to identify groups of individuals based on their point of view on these drugs; and finally, to explore the experiences of patients with chronic non-malignant low back pain in Spain undergoing long-term treatment (>3 months) with opioids. Methods In the first study of the thesis, a systematic review of the current literature and meta-analysis were performed using two databases (PubMed and SCOPUS). For this purpose, original crosssectional studies published in English or Spanish between 2009 and 2019 with the main objective of determining the prevalence of opioid use in CNCP patients were included. Search terms and search strategies were adapted to each database. The articles included in the meta-analysis were stratified according to the source of the sample, the type of pain, and the duration of the opioid treatment. The second paper of the thesis is a descriptive study using retrospective annual data from 2008 to 2017 in the general population of Spain and the United States. Information on the population and opioid-related deaths stratified by age and sex was obtained from the Spanish National Statistics Institute and from the Centers for Disease Control and Prevention (CDC) WONDER Multiple Cause of Death Database, according to the ICD-10 codes. Years of life lost, crude an…
abstract: Aims The general aim of this thesis was to study the situation of opioid treatments for chronic noncancer pain (CNCP). The specific aims were: first, to determine and synthesize the prevalence of the therapeutic use of opioids in patients with CNCP, and to analyze the factors associated with their use through a systematic review of the literature and a meta-analysis; second, to investigate the evolution of opioid-related mortality and potential years of life lost in the general population in Spain from 2008 to 2017 and to compare the results by gender and age with the United States; third, to describe the current perspective of the Spanish population toward opioid use in the treatment of pain and to identify groups of individuals based on their point of view on these drugs; and finally, to explore the experiences of patients with chronic non-malignant low back pain in Spain undergoing long-term treatment (>3 months) with opioids. Methods In the first study of the thesis, a systematic review of the current literature and meta-analysis were performed using two databases (PubMed and SCOPUS). For this purpose, original crosssectional studies published in English or Spanish between 2009 and 2019 with the main objective of determining the prevalence of opioid use in CNCP patients were included. Search terms and search strategies were adapted to each database. The articles included in the meta-analysis were stratified according to the source of the sample, the type of pain, and the duration of the opioid treatment. The second paper of the thesis is a descriptive study using retrospective annual data from 2008 to 2017 in the general population of Spain and the United States. Information on the population and opioid-related deaths stratified by age and sex was obtained from the Spanish National Statistics Institute and from the Centers for Disease Control and Prevention (CDC) WONDER Multiple Cause of Death Database, according to the ICD-10 codes. Years of life lost, crude an…
author: Sola Perea, Helena de
language: eng
keywords: Opioids, Chronic pain, Prevalence, Mortality, Experiences
license: http://creativecommons.org/licenses/by-nc-nd/4.0/
date published: 2020-07-07
date modified: 2026-07-24T01:29:50Z
provider: Universidad de Cadiz
publisher: Networked Digital Library of Theses and Dissertations
type: WebPage
source organization: Universidad de Cadiz

PropertyValue
property ID: Handle
value: http://hdl.handle.net/10498/23642