{"id":{"repo_id":"buffalo","oai_identifier":"oai:ubir.buffalo.edu:10477/79977"},"canonical_url":"https://search.dev.ndltd.org/etd/buffalo/oai:ubir.buffalo.edu:10477/79977","repository":{"repo_id":"buffalo","name":"Buffalo","base_url":"https://ubir.buffalo.edu/oai/request"},"display":{"title":"Relationship Between Hypothyroid Disease and Periodontitis","abstract":"M.S.","abstract_html":"M.S.","abstract_has_math":false,"creators":["Aldulaijan, Hajer"],"institution":"State University of New York at Buffalo","degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":null,"school":null,"contributors":["Yerke, Lisa","Oral Sciences"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2019,"date_issued":"2019-07-30T15:11:32Z","date_published":"2019-07-30T15:11:32Z","updated_at":"2026-07-27T19:05:21Z","subjects":["dentistry"],"languages":["eng"],"rights":["Users of works found in University at Buffalo Institutional Repository (UBIR) are responsible for identifying and contacting the copyright owner for permission to reuse. University at Buffalo Libraries do not manage rights for copyright-protected works and cannot assist with permissions.","Copyright retained by author."],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"http://hdl.handle.net/10477/79977","outbound_label":"Handle","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Yerke, Lisa","Oral Sciences"]},{"key":"dc:creator","label":"Author","values":["Aldulaijan, Hajer"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date","label":"Dc Date","values":["2019-07-30T15:11:32Z","2019","2019-05-16 14:25:36"]},{"key":"dc:publisher","label":"Institution","values":["State University of New York at Buffalo"]},{"key":"dc:type","label":"Dc Type","values":["Text","Thesis"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["dentistry"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language","label":"Dc Language","values":["eng"]},{"key":"dc:rights","label":"Dc Rights","values":["Users of works found in University at Buffalo Institutional Repository (UBIR) are responsible for identifying and contacting the copyright owner for permission to reuse. University at Buffalo Libraries do not manage rights for copyright-protected works and cannot assist with permissions.","Copyright retained by author."]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["http://hdl.handle.net/10477/79977"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["M.S.","Background: The potential association between periodontitis and a variety of immunologic and inflammatory conditions provides a foundation for a possible relationship between hypothyroidism and periodontitis. A scoping review was performed to categorize and evaluate the existing literature regarding the potential relationship between those conditions. Methods: We used a modified approach to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) by searching five databases in addition to the grey literature. Keywords for both periodontal disease and hypothyroidism in the title and abstract fields, including subject terms from the database thesaurus when possible, were used to search the existing literature for publications relevant to evaluation of the thyroid-periodontitis relationship. No date or language restrictions were applied. Results: The authors screened 847 unique publications from an initial search September 4th, 2018, and a supplemental search on April 26th, 2019, which, after applying inclusion and exclusion criteria, yielded 29 publications (28 full-length papers and one abstract), which were further analyzed for relevance and applicability. Most of the included papers were cross-sectional studies (n= 14), with five of them being retrospective chart reviews. Only one retrospective cohort study, one intervention study, three case-control studies, two review papers, three case reports, and four animal studies, were identified after review of the literature, in addition to one abstract. However, following critical analysis, only three papers and one abstract were used to further assess the hypothyroid-periodontitis relationship. Conclusions: There are very few high-quality studies describing the potential association between hypothyroidism and periodontitis, with most of the available literature consisting of retrospective cross-sectional studies and chart reviews. In general, and among the included papers with the fewest confounding factors, a positive relationship between hypothyroidism and periodontitis was found. Further well-controlled, prospective clinical and immunologic studies will be required to confirm that relationship, to measure the strength of any association with disease severity, to establish causality, and to establish the role of either disease in the pathogenesis of the other."]},{"key":"dc:format","label":"Dc Format","values":["application/pdf"]},{"key":"dc:title","label":"Title","values":["Relationship Between Hypothyroid Disease and Periodontitis"]}]}],"canonical_facts":{"dc:contributor":["Yerke, Lisa","Oral Sciences"],"dc:creator":["Aldulaijan, Hajer"],"dc:date":["2019-07-30T15:11:32Z","2019","2019-05-16 14:25:36"],"dc:description":["M.S.","Background: The potential association between periodontitis and a variety of immunologic and inflammatory conditions provides a foundation for a possible relationship between hypothyroidism and periodontitis. A scoping review was performed to categorize and evaluate the existing literature regarding the potential relationship between those conditions. Methods: We used a modified approach to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) by searching five databases in addition to the grey literature. Keywords for both periodontal disease and hypothyroidism in the title and abstract fields, including subject terms from the database thesaurus when possible, were used to search the existing literature for publications relevant to evaluation of the thyroid-periodontitis relationship. No date or language restrictions were applied. Results: The authors screened 847 unique publications from an initial search September 4th, 2018, and a supplemental search on April 26th, 2019, which, after applying inclusion and exclusion criteria, yielded 29 publications (28 full-length papers and one abstract), which were further analyzed for relevance and applicability. Most of the included papers were cross-sectional studies (n= 14), with five of them being retrospective chart reviews. Only one retrospective cohort study, one intervention study, three case-control studies, two review papers, three case reports, and four animal studies, were identified after review of the literature, in addition to one abstract. However, following critical analysis, only three papers and one abstract were used to further assess the hypothyroid-periodontitis relationship. Conclusions: There are very few high-quality studies describing the potential association between hypothyroidism and periodontitis, with most of the available literature consisting of retrospective cross-sectional studies and chart reviews. In general, and among the included papers with the fewest confounding factors, a positive relationship between hypothyroidism and periodontitis was found. Further well-controlled, prospective clinical and immunologic studies will be required to confirm that relationship, to measure the strength of any association with disease severity, to establish causality, and to establish the role of either disease in the pathogenesis of the other."],"dc:format":["application/pdf"],"dc:identifier":["http://hdl.handle.net/10477/79977"],"dc:language":["eng"],"dc:publisher":["State University of New York at Buffalo"],"dc:rights":["Users of works found in University at Buffalo Institutional Repository (UBIR) are responsible for identifying and contacting the copyright owner for permission to reuse. University at Buffalo Libraries do not manage rights for copyright-protected works and cannot assist with permissions.","Copyright retained by author."],"dc:subject":["dentistry"],"dc:title":["Relationship Between Hypothyroid Disease and Periodontitis"],"dc:type":["Text","Thesis"]},"updated_at":"2026-07-27T19:05:21Z"}