{"id":{"repo_id":"buffalo","oai_identifier":"oai:ubir.buffalo.edu:10477/79846"},"canonical_url":"https://search.dev.ndltd.org/etd/buffalo/oai:ubir.buffalo.edu:10477/79846","repository":{"repo_id":"buffalo","name":"Buffalo","base_url":"https://ubir.buffalo.edu/oai/request"},"display":{"title":"Understanding the Effects of Engineered Nanomaterials on Mammalian Cells and Plants Using a Mass Spectrometry Based Approaches","abstract":"Ph.D.","abstract_html":"Ph.D.","abstract_has_math":false,"creators":["Chavez Soria, Nita; 0000-0003-2303-6914"],"institution":"State University of New York at Buffalo","degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":null,"school":null,"contributors":["Aga, Diana","Chemistry"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2019,"date_issued":"2019-07-29T20:41:42Z","date_published":"2019-07-29T20:41:42Z","updated_at":"2026-07-27T19:05:19Z","subjects":["chemistry","environmental studies","nanotechnology"],"languages":["eng"],"rights":["Users of works found in University at Buffalo Institutional Repository (UBIR) are responsible for identifying and contacting the copyright owner for permission to reuse. University at Buffalo Libraries do not manage rights for copyright-protected works and cannot assist with permissions.","Copyright retained by author."],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"http://hdl.handle.net/10477/79846","outbound_label":"Handle","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Aga, Diana","Chemistry"]},{"key":"dc:creator","label":"Author","values":["Chavez Soria, Nita; 0000-0003-2303-6914"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date","label":"Dc Date","values":["2019-07-29T20:41:42Z","2019","2019-05-14 19:37:29"]},{"key":"dc:publisher","label":"Institution","values":["State University of New York at Buffalo"]},{"key":"dc:type","label":"Dc Type","values":["Text","Dissertation"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["chemistry","environmental studies","nanotechnology"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language","label":"Dc Language","values":["eng"]},{"key":"dc:rights","label":"Dc Rights","values":["Users of works found in University at Buffalo Institutional Repository (UBIR) are responsible for identifying and contacting the copyright owner for permission to reuse. University at Buffalo Libraries do not manage rights for copyright-protected works and cannot assist with permissions.","Copyright retained by author."]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["http://hdl.handle.net/10477/79846"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["Ph.D.","Nanotechnology focuses on the development and application of materials in the nanoscale range. Engineered nanomaterials (ENMs) are usually defined as particles of 1-100 nm in size in at least one dimension, which have been developed for specific applications. New ENMs have allowed for applications in agriculture, environmental remediation, medicine, and production of consumer goods. However, the adverse effects to humans, animals and the environment remain largely unknown. Due to the complex nature of ENMs, there is no single analytical characterization technique or toxicity protocol available to help understand the fate and adverse effects of ENMs. Thus, in this dissertation, a metabolomics approach was applied to gain a deeper understanding on the effects of ENMs in different biological organisms at the metabolome level, to determine the uptake mechanism of nanoparticles (NPs) as well as identify potential biomarkers of exposure.","**To request an accessible version of the file(s) associated with this item, contact library@buffalo.edu. Please include the item's persistent URL [http://hdl.handle.net/. . .] in your request.**"]},{"key":"dc:format","label":"Dc Format","values":["application/pdf"]},{"key":"dc:title","label":"Title","values":["Understanding the Effects of Engineered Nanomaterials on Mammalian Cells and Plants Using a Mass Spectrometry Based Approaches"]}]}],"canonical_facts":{"dc:contributor":["Aga, Diana","Chemistry"],"dc:creator":["Chavez Soria, Nita; 0000-0003-2303-6914"],"dc:date":["2019-07-29T20:41:42Z","2019","2019-05-14 19:37:29"],"dc:description":["Ph.D.","Nanotechnology focuses on the development and application of materials in the nanoscale range. Engineered nanomaterials (ENMs) are usually defined as particles of 1-100 nm in size in at least one dimension, which have been developed for specific applications. New ENMs have allowed for applications in agriculture, environmental remediation, medicine, and production of consumer goods. However, the adverse effects to humans, animals and the environment remain largely unknown. Due to the complex nature of ENMs, there is no single analytical characterization technique or toxicity protocol available to help understand the fate and adverse effects of ENMs. Thus, in this dissertation, a metabolomics approach was applied to gain a deeper understanding on the effects of ENMs in different biological organisms at the metabolome level, to determine the uptake mechanism of nanoparticles (NPs) as well as identify potential biomarkers of exposure.","**To request an accessible version of the file(s) associated with this item, contact library@buffalo.edu. Please include the item's persistent URL [http://hdl.handle.net/. . .] in your request.**"],"dc:format":["application/pdf"],"dc:identifier":["http://hdl.handle.net/10477/79846"],"dc:language":["eng"],"dc:publisher":["State University of New York at Buffalo"],"dc:rights":["Users of works found in University at Buffalo Institutional Repository (UBIR) are responsible for identifying and contacting the copyright owner for permission to reuse. University at Buffalo Libraries do not manage rights for copyright-protected works and cannot assist with permissions.","Copyright retained by author."],"dc:subject":["chemistry","environmental studies","nanotechnology"],"dc:title":["Understanding the Effects of Engineered Nanomaterials on Mammalian Cells and Plants Using a Mass Spectrometry Based Approaches"],"dc:type":["Text","Dissertation"]},"updated_at":"2026-07-27T19:05:19Z"}