{"id":{"repo_id":"buffalo","oai_identifier":"oai:ubir.buffalo.edu:10477/78120"},"canonical_url":"https://search.dev.ndltd.org/etd/buffalo/oai:ubir.buffalo.edu:10477/78120","repository":{"repo_id":"buffalo","name":"Buffalo","base_url":"https://ubir.buffalo.edu/oai/request"},"display":{"title":"Caffeine Intake and Invasive Breast Cancer Incidence Among Postmenopausal Women in the Women's Health Initiative","abstract":"M.S.","abstract_html":"M.S.","abstract_has_math":false,"creators":["Zheng, Kan Hong"],"institution":"State University of New York at Buffalo","degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":null,"school":null,"contributors":["Mu, Lina","Epidemiology and Environmental Health"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2018,"date_issued":"2018-06-28T20:34:22Z","date_published":"2018-06-28T20:34:22Z","updated_at":"2026-07-27T19:05:09Z","subjects":["epidemiology","public health"],"languages":["eng"],"rights":["Users of works found in University at Buffalo Institutional Repository (UBIR) are responsible for identifying and contacting the copyright owner for permission to reuse. University at Buffalo Libraries do not manage rights for copyright-protected works and cannot assist with permissions.","Copyright retained by author."],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"http://hdl.handle.net/10477/78120","outbound_label":"Handle","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Mu, Lina","Epidemiology and Environmental Health"]},{"key":"dc:creator","label":"Author","values":["Zheng, Kan Hong"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date","label":"Dc Date","values":["2018-06-28T20:34:22Z","2018","2018-05-18 11:33:02"]},{"key":"dc:publisher","label":"Institution","values":["State University of New York at Buffalo"]},{"key":"dc:type","label":"Dc Type","values":["Text","Thesis"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["epidemiology","public health"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language","label":"Dc Language","values":["eng"]},{"key":"dc:rights","label":"Dc Rights","values":["Users of works found in University at Buffalo Institutional Repository (UBIR) are responsible for identifying and contacting the copyright owner for permission to reuse. University at Buffalo Libraries do not manage rights for copyright-protected works and cannot assist with permissions.","Copyright retained by author."]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["http://hdl.handle.net/10477/78120"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["M.S.","Background: Results of research on the effects of caffeine consumption and invasive breast cancer remains inconsistent. The aim of this study was to determine the association between caffeine intake from coffee and tea on incident invasive breast cancer in a large cohort of postmenopausal women. Methods: This analysis included 79,871 women without previous invasive breast cancer in the Women’s Health Initiative Observational Study prospective cohort. Coffee and tea intake were self-reported in a baseline questionnaire. Cox proportional hazard models were used to estimate crude and multivariate-adjusted hazards ratios (HR) and 95% confidence intervals (CIs) for invasive breast cancer incidence. Subgroup analyses by beverage type, age, race/ethnicity, smoking status, BMI, sleep duration, history of hormone therapy use, and invasive breast cancer receptor subtypes were also assessed. Results: A total of 4,719 incident cases of invasive breast cancer were identified with a mean follow-up time of 13.5 years. No significant association was found between overall reported caffeine intake from coffee and tea and invasive breast cancer incidence. In the beverage-specific analysis, participants consuming 2-3 cups/day of caffeinated or decaffeinated coffee, compared to non-drinkers, were at increased risk of invasive breast cancer in a multivariate model adjusting for age, race/ethnicity, education, and other caffeinated beverages (caffeinated coffee HR = 1.12, 95% CI = 1.02-1.24; decaffeinated coffee HR = 1.24, 95% CI = 1.09-1.41). Invasive breast cancer risk was not associated with tea consumption. In analysis of invasive breast cancer receptor subtypes, there was decreased risk of ER+/PR- breast cancer among those in the highest quartile (279 – 736 mg/d) of caffeine consumption compared to the lowest (0 – 93 mg/d) (HR = 0.74, 95% CI = 0.59, 0.93)."]},{"key":"dc:format","label":"Dc Format","values":["application/pdf"]},{"key":"dc:title","label":"Title","values":["Caffeine Intake and Invasive Breast Cancer Incidence Among Postmenopausal Women in the Women's Health Initiative"]}]}],"canonical_facts":{"dc:contributor":["Mu, Lina","Epidemiology and Environmental Health"],"dc:creator":["Zheng, Kan Hong"],"dc:date":["2018-06-28T20:34:22Z","2018","2018-05-18 11:33:02"],"dc:description":["M.S.","Background: Results of research on the effects of caffeine consumption and invasive breast cancer remains inconsistent. The aim of this study was to determine the association between caffeine intake from coffee and tea on incident invasive breast cancer in a large cohort of postmenopausal women. Methods: This analysis included 79,871 women without previous invasive breast cancer in the Women’s Health Initiative Observational Study prospective cohort. Coffee and tea intake were self-reported in a baseline questionnaire. Cox proportional hazard models were used to estimate crude and multivariate-adjusted hazards ratios (HR) and 95% confidence intervals (CIs) for invasive breast cancer incidence. Subgroup analyses by beverage type, age, race/ethnicity, smoking status, BMI, sleep duration, history of hormone therapy use, and invasive breast cancer receptor subtypes were also assessed. Results: A total of 4,719 incident cases of invasive breast cancer were identified with a mean follow-up time of 13.5 years. No significant association was found between overall reported caffeine intake from coffee and tea and invasive breast cancer incidence. In the beverage-specific analysis, participants consuming 2-3 cups/day of caffeinated or decaffeinated coffee, compared to non-drinkers, were at increased risk of invasive breast cancer in a multivariate model adjusting for age, race/ethnicity, education, and other caffeinated beverages (caffeinated coffee HR = 1.12, 95% CI = 1.02-1.24; decaffeinated coffee HR = 1.24, 95% CI = 1.09-1.41). Invasive breast cancer risk was not associated with tea consumption. In analysis of invasive breast cancer receptor subtypes, there was decreased risk of ER+/PR- breast cancer among those in the highest quartile (279 – 736 mg/d) of caffeine consumption compared to the lowest (0 – 93 mg/d) (HR = 0.74, 95% CI = 0.59, 0.93)."],"dc:format":["application/pdf"],"dc:identifier":["http://hdl.handle.net/10477/78120"],"dc:language":["eng"],"dc:publisher":["State University of New York at Buffalo"],"dc:rights":["Users of works found in University at Buffalo Institutional Repository (UBIR) are responsible for identifying and contacting the copyright owner for permission to reuse. University at Buffalo Libraries do not manage rights for copyright-protected works and cannot assist with permissions.","Copyright retained by author."],"dc:subject":["epidemiology","public health"],"dc:title":["Caffeine Intake and Invasive Breast Cancer Incidence Among Postmenopausal Women in the Women's Health Initiative"],"dc:type":["Text","Thesis"]},"updated_at":"2026-07-27T19:05:09Z"}