{"id":{"repo_id":"buffalo","oai_identifier":"oai:ubir.buffalo.edu:10477/78029"},"canonical_url":"https://search.dev.ndltd.org/etd/buffalo/oai:ubir.buffalo.edu:10477/78029","repository":{"repo_id":"buffalo","name":"Buffalo","base_url":"https://ubir.buffalo.edu/oai/request"},"display":{"title":"Diet Patterns and Incident Age-Related Macular Degeneration in the Atherosclerosis Risk in Communities (ARIC) Study","abstract":"M.S.","abstract_html":"M.S.","abstract_has_math":false,"creators":["Dighe, Shruti; 0000-0002-6654-521X"],"institution":"State University of New York at Buffalo","degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":null,"school":null,"contributors":["Millen, Amy","Epidemiology and Environmental Health"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2018,"date_issued":"2018-06-28T20:32:52Z","date_published":"2018-06-28T20:32:52Z","updated_at":"2026-07-27T19:05:07Z","subjects":["epidemiology"],"languages":["eng"],"rights":["Users of works found in University at Buffalo Institutional Repository (UBIR) are responsible for identifying and contacting the copyright owner for permission to reuse. University at Buffalo Libraries do not manage rights for copyright-protected works and cannot assist with permissions.","Copyright retained by author."],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"http://hdl.handle.net/10477/78029","outbound_label":"Handle","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Millen, Amy","Epidemiology and Environmental Health"]},{"key":"dc:creator","label":"Author","values":["Dighe, Shruti; 0000-0002-6654-521X"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date","label":"Dc Date","values":["2018-06-28T20:32:52Z","2018","2018-05-15 18:14:09"]},{"key":"dc:publisher","label":"Institution","values":["State University of New York at Buffalo"]},{"key":"dc:type","label":"Dc Type","values":["Text","Thesis"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["epidemiology"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language","label":"Dc Language","values":["eng"]},{"key":"dc:rights","label":"Dc Rights","values":["Users of works found in University at Buffalo Institutional Repository (UBIR) are responsible for identifying and contacting the copyright owner for permission to reuse. University at Buffalo Libraries do not manage rights for copyright-protected works and cannot assist with permissions.","Copyright retained by author."]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["http://hdl.handle.net/10477/78029"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["M.S.","Objective: Age-related macular degeneration (AMD) is the leading cause of irreversible vision loss among the elderly. The aim of our study was to determine the association between dietary patterns and the 18-year incidence of AMD. Methods: ARIC participants (n=1,278) with change in retinal photographs taken at Visit 3 (1993-95) and Visit 5 (2011-13) were graded side-by-side to determine incident AMD (any =144; early=117; late=27). A 66 line-item food frequency questionnaire, at Visit 1 (1987-89) and Visit 3, was used to identify 29 food groups. Principal component analysis was used to derive dietary patterns from the average of Visits 1 and 3. Odds ratios (ORs) and 95% confidence intervals (CIs) for any, early and late incident AMD by tertiles of pattern scores were estimated with logistic regression, adjusting for age, race, education, total calories and smoking status. Median pattern cut points were used for late AMD. Ptrend was estimated using continuous scores. Results: Western and Prudent patterns were identified. Adjusted OR (95% CIs) for any incident AMD among participants in tertile 3 compared to 1 was 1.43 (0.83-2.46), (Ptrend=0.29) and 0.90 (0.56-1.46), (Ptrend=0.68) for the Western and Prudent patterns, respectively. No significant associations were found with incident early AMD. For incident late AMD, adjusted OR (95% CIs) for participants with scores above compared to below the median were 3.45 (1.33-8.87) (Ptrend=0.01) and 0.56 (0.24-1.33) (Ptrend=0.05) for the Western and the Prudent patterns, respectively. Conclusions: Diet patterns are not significantly associated with any or early incident AMD; however, a Western pattern may be a risk factor for incident late AMD. This study is limited by its number of incident cases."]},{"key":"dc:format","label":"Dc Format","values":["application/pdf"]},{"key":"dc:title","label":"Title","values":["Diet Patterns and Incident Age-Related Macular Degeneration in the Atherosclerosis Risk in Communities (ARIC) Study"]}]}],"canonical_facts":{"dc:contributor":["Millen, Amy","Epidemiology and Environmental Health"],"dc:creator":["Dighe, Shruti; 0000-0002-6654-521X"],"dc:date":["2018-06-28T20:32:52Z","2018","2018-05-15 18:14:09"],"dc:description":["M.S.","Objective: Age-related macular degeneration (AMD) is the leading cause of irreversible vision loss among the elderly. The aim of our study was to determine the association between dietary patterns and the 18-year incidence of AMD. Methods: ARIC participants (n=1,278) with change in retinal photographs taken at Visit 3 (1993-95) and Visit 5 (2011-13) were graded side-by-side to determine incident AMD (any =144; early=117; late=27). A 66 line-item food frequency questionnaire, at Visit 1 (1987-89) and Visit 3, was used to identify 29 food groups. Principal component analysis was used to derive dietary patterns from the average of Visits 1 and 3. Odds ratios (ORs) and 95% confidence intervals (CIs) for any, early and late incident AMD by tertiles of pattern scores were estimated with logistic regression, adjusting for age, race, education, total calories and smoking status. Median pattern cut points were used for late AMD. Ptrend was estimated using continuous scores. Results: Western and Prudent patterns were identified. Adjusted OR (95% CIs) for any incident AMD among participants in tertile 3 compared to 1 was 1.43 (0.83-2.46), (Ptrend=0.29) and 0.90 (0.56-1.46), (Ptrend=0.68) for the Western and Prudent patterns, respectively. No significant associations were found with incident early AMD. For incident late AMD, adjusted OR (95% CIs) for participants with scores above compared to below the median were 3.45 (1.33-8.87) (Ptrend=0.01) and 0.56 (0.24-1.33) (Ptrend=0.05) for the Western and the Prudent patterns, respectively. Conclusions: Diet patterns are not significantly associated with any or early incident AMD; however, a Western pattern may be a risk factor for incident late AMD. This study is limited by its number of incident cases."],"dc:format":["application/pdf"],"dc:identifier":["http://hdl.handle.net/10477/78029"],"dc:language":["eng"],"dc:publisher":["State University of New York at Buffalo"],"dc:rights":["Users of works found in University at Buffalo Institutional Repository (UBIR) are responsible for identifying and contacting the copyright owner for permission to reuse. University at Buffalo Libraries do not manage rights for copyright-protected works and cannot assist with permissions.","Copyright retained by author."],"dc:subject":["epidemiology"],"dc:title":["Diet Patterns and Incident Age-Related Macular Degeneration in the Atherosclerosis Risk in Communities (ARIC) Study"],"dc:type":["Text","Thesis"]},"updated_at":"2026-07-27T19:05:07Z"}