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Boston University

Generative AI for osteoarthritis imaging: CycleGAN-based synthesis and U-net3D segmentation

Abstract

dc:description.abstract

Osteoarthritis (OA) is one of the leading diseases in aging people. However, we still don’t know what causes the disease and the efficient treatment for it. In this thesis, we deploy a generative artificial intelligence, which has become a tool and a new trend in AI. We design generative AI models for medical imaging, particularly for lowering data imbalance and increasing diagnostic accuracy. This thesis investigates the application of CycleGAN and Unet3D in two medical imaging tasks: hand osteoarthritis (HOA) and knee effusion. The experiment results demonstrate promising findings in improving the accuracy of image classification and segmentation tasks.

Author and committee

dc:creator, dc:contributor.*
Author dc:creator
  • Cao, Zhen
Advisor dc:contributor.advisor
  • Zhang, Ming

Subjects

dc:subject × 6

Rights

dc:rights
Statement dc:rights
  • Attribution 4.0 International
Language dc:language.iso
en_US

Identifiers

dc:identifier.*
Handle dc:identifier.uri
https://hdl.handle.net/2144/53162
OAI identifier oai:identifier
oai:open.bu.edu:2144/53162

Chain of custody

source
Harvested from
Boston University
Base URL
open.bu.edu/oai/request
Last updated
2026-07-24
Source record
OAI-PMH GetRecord
citation

Cao, Zhen. Generative AI for osteoarthritis imaging: CycleGAN-based synthesis and U-net3D segmentation. 2025. https://hdl.handle.net/2144/53162