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Brock University
NMR characterization of chlorhexidine in lipid-based formulations /
Abstract
dc:description.abstractA mixture of Chlorhexidine digluconate (CHG) with glycerophospholipid 1,2-dimyristoyl- <^54-glycero-3-phospocholine (DMPC-rf54) was analysed using ^H nuclear magnetic resonance. To analyze powder spectra, the de-Pake-ing technique was used. The method is able to extract simultaneously both the orientation distribution function and the anisotropy distribution function. The spectral moments, average order parameter profiles, and longitudinal and transverse relaxation times were used to explore the structural phase behaviour of various DMPC/CHG mixtures in the temperature range 5-60°C.
Degree
thesis:*- Name thesis:degree_name
- M.Sc. Physics
- Level thesis:degree_level
- Masters
- Discipline thesis:degree_discipline
- Faculty of Mathematics and Science
- Department dc:contributor.department
- Department of Physics
- Grantor
- Brock University
- Year dc:date.issued
- 2004
Author and committee
dc:creator, dc:contributor.*- Author dc:creator
-
- Trsková, Zuzana.
Subjects
dc:subject × 3Rights
- Language dc:language.iso
- eng
Identifiers
dc:identifier.*- Handle dc:identifier.uri
- http://hdl.handle.net/10464/2262
- OAI identifier oai:identifier
- oai:brocku.scholaris.ca:10464/2262