{"id":{"repo_id":"brazil-ufpb","oai_identifier":"oai:repositorio.ufpb.br:123456789/564"},"canonical_url":"https://search.dev.ndltd.org/etd/brazil-ufpb/oai:repositorio.ufpb.br:123456789/564","repository":{"repo_id":"brazil-ufpb","name":"Brazil UFPB","base_url":"https://repositorio.ufpb.br/oai/request"},"display":{"title":"Biomarcadores relevantes para diagnóstico precoce e prevenção de doenças cardiovasculares.","abstract":"Cardiovasc ular diseases are the major cause of death worldwide . Atherosclerosis is a chronic inflammatory process of the blood vessels responsible for the origin of the largest number in morbidity and mortality from cardiovascular diseases . The traditional risk fact ors are insufficient in predicting large proportion of cardiovascular events , requiring to improve the predictive power of these and the discovery of new biomarkers effective . C - reactive protein , homocysteine , fibrinogen , D - dimer , lipoprotein( a), lipoprotein associated phospholipase A2 , apolipoprotein AI / apolipoprotein B , natriuretic peptides and myeloperoxidase are biomarkers nontraditional whose predictive power and clinical application are under discuss ion . CRP, homocysteine , Lp (a) Lp - PLA2 and MPO act in pathophysiological mechanisms stimulating the atherogenic and thrombogenic process. The measurement of D - dimer represents the formation and degradation of the fibrin clot in the dynamics of blood coag ulation. Levels of apoB and apoA - I represent effective atherogenic and anti - atherogenic parameters of cardiovascular diseases . Natriuretic peptides act in cardiovascular and renal physiology regulating blood pressure and blood volume . The predictive power of these biomarkers is based on the epidemiology of scientific literature. Significant advance in understanding the mechanisms atherosclerotic occurred , but much should be revealed in the field of epidemiology and pathophysiology towards reducing the damag e caused by cardiovascular diseases in health care","abstract_html":"Cardiovasc ular diseases are the major cause of death worldwide . Atherosclerosis is a chronic inflammatory process of the blood vessels responsible for the origin of the largest number in morbidity and mortality from cardiovascular diseases . The traditional risk fact ors are insufficient in predicting large proportion of cardiovascular events , requiring to improve the predictive power of these and the discovery of new biomarkers effective . C - reactive protein , homocysteine , fibrinogen , D - dimer , lipoprotein( a), lipoprotein associated phospholipase A2 , apolipoprotein AI / apolipoprotein B , natriuretic peptides and myeloperoxidase are biomarkers nontraditional whose predictive power and clinical application are under discuss ion . CRP, homocysteine , Lp (a) Lp - PLA2 and MPO act in pathophysiological mechanisms stimulating the atherogenic and thrombogenic process. The measurement of D - dimer represents the formation and degradation of the fibrin clot in the dynamics of blood coag ulation. Levels of apoB and apoA - I represent effective atherogenic and anti - atherogenic parameters of cardiovascular diseases . Natriuretic peptides act in cardiovascular and renal physiology regulating blood pressure and blood volume . The predictive power of these biomarkers is based on the epidemiology of scientific literature. Significant advance in understanding the mechanisms atherosclerotic occurred , but much should be revealed in the field of epidemiology and pathophysiology towards reducing the damag e caused by cardiovascular diseases in health care","abstract_has_math":false,"creators":["Queiroz, Júlio César Souto"],"institution":"Universidade Federal da Paraíba","degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":null,"school":null,"contributors":[],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2014,"date_issued":"2014-07-15","date_published":"2014-07-15","updated_at":"2026-07-24T01:17:57Z","subjects":["Doenças cardiovascular","Biiomarcadores","Diagnóstico","Risco cardiovascular","Prevenção"],"languages":["pt"],"rights":[],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"https://repositorio.ufpb.br/jspui/handle/123456789/564","outbound_label":"Repository record","outbound_source":"dc:identifier.uri"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:creator","label":"Author","values":["Queiroz, Júlio César Souto"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.accessioned","label":"Dc Date Accessioned","values":["2014-07-15T11:39:53Z"]},{"key":"dc:date.available","label":"Dc Date Available","values":["2014-07-15T11:39:53Z"]},{"key":"dc:date.issued","label":"Date","values":["2014-07-15"]},{"key":"dc:publisher","label":"Institution","values":["Universidade Federal da Paraíba"]},{"key":"dc:type","label":"Dc Type","values":["TCC"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Doenças cardiovascular","Biiomarcadores","Diagnóstico","Risco cardiovascular","Prevenção"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language.iso","label":"Language (ISO)","values":["pt"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier.uri","label":"Identifier URI","values":["https://repositorio.ufpb.br/jspui/handle/123456789/564"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["Cardiovasc ular diseases are the major cause of death worldwide . Atherosclerosis is a chronic inflammatory process of the blood vessels responsible for the origin of the largest number in morbidity and mortality from cardiovascular diseases . The traditional risk fact ors are insufficient in predicting large proportion of cardiovascular events , requiring to improve the predictive power of these and the discovery of new biomarkers effective . C - reactive protein , homocysteine , fibrinogen , D - dimer , lipoprotein( a), lipoprotein associated phospholipase A2 , apolipoprotein AI / apolipoprotein B , natriuretic peptides and myeloperoxidase are biomarkers nontraditional whose predictive power and clinical application are under discuss ion . CRP, homocysteine , Lp (a) Lp - PLA2 and MPO act in pathophysiological mechanisms stimulating the atherogenic and thrombogenic process. The measurement of D - dimer represents the formation and degradation of the fibrin clot in the dynamics of blood coag ulation. Levels of apoB and apoA - I represent effective atherogenic and anti - atherogenic parameters of cardiovascular diseases . Natriuretic peptides act in cardiovascular and renal physiology regulating blood pressure and blood volume . The predictive power of these biomarkers is based on the epidemiology of scientific literature. Significant advance in understanding the mechanisms atherosclerotic occurred , but much should be revealed in the field of epidemiology and pathophysiology towards reducing the damag e caused by cardiovascular diseases in health care"]},{"key":"dc:title","label":"Title","values":["Biomarcadores relevantes para diagnóstico precoce e prevenção de doenças cardiovasculares."]}]}],"canonical_facts":{"dc:creator":["Queiroz, Júlio César Souto"],"dc:date.accessioned":["2014-07-15T11:39:53Z"],"dc:date.available":["2014-07-15T11:39:53Z"],"dc:date.issued":["2014-07-15"],"dc:description.abstract":["Cardiovasc ular diseases are the major cause of death worldwide . Atherosclerosis is a chronic inflammatory process of the blood vessels responsible for the origin of the largest number in morbidity and mortality from cardiovascular diseases . The traditional risk fact ors are insufficient in predicting large proportion of cardiovascular events , requiring to improve the predictive power of these and the discovery of new biomarkers effective . C - reactive protein , homocysteine , fibrinogen , D - dimer , lipoprotein( a), lipoprotein associated phospholipase A2 , apolipoprotein AI / apolipoprotein B , natriuretic peptides and myeloperoxidase are biomarkers nontraditional whose predictive power and clinical application are under discuss ion . CRP, homocysteine , Lp (a) Lp - PLA2 and MPO act in pathophysiological mechanisms stimulating the atherogenic and thrombogenic process. The measurement of D - dimer represents the formation and degradation of the fibrin clot in the dynamics of blood coag ulation. Levels of apoB and apoA - I represent effective atherogenic and anti - atherogenic parameters of cardiovascular diseases . Natriuretic peptides act in cardiovascular and renal physiology regulating blood pressure and blood volume . The predictive power of these biomarkers is based on the epidemiology of scientific literature. Significant advance in understanding the mechanisms atherosclerotic occurred , but much should be revealed in the field of epidemiology and pathophysiology towards reducing the damag e caused by cardiovascular diseases in health care"],"dc:identifier.uri":["https://repositorio.ufpb.br/jspui/handle/123456789/564"],"dc:language.iso":["pt"],"dc:publisher":["Universidade Federal da Paraíba"],"dc:subject":["Doenças cardiovascular","Biiomarcadores","Diagnóstico","Risco cardiovascular","Prevenção"],"dc:title":["Biomarcadores relevantes para diagnóstico precoce e prevenção de doenças cardiovasculares."],"dc:type":["TCC"]},"updated_at":"2026-07-24T01:17:57Z"}