Abstract
dc:description.abstractThis study was done to assess the safety and efficiency of cell therapy for pseudoarthrosis. Implant of the bone marrow aspirate was compared to mononuclear cells purified extemnporaneously using the Sepax® equipment. Seven patients with nonunion of the tibia or femur were treated. Five received a percutaneous infusion of autologous bone marrow aspirated from the iliac crest, and two received autologous bone marrow mononuclear cells separated from the aspirate by Sepax®. The primary fixation method was unchanged, and the nonunion focus was not exposed. Physical examination and radiographies were done 2, 4 and 6 months after the treatment by the same physician. After the consolidation of the fracture the satisfaction of the patients was estimated using a 0 to 10 scale. No complications occurred as a result of the referred procedures. Bone consolidation was obtained in all cases within 3 to 24 weeks. The degree of patient satisfaction before and after bone consolidation was assessed, with the average value increasing from two to nine (p=0.0156). The proposed method is effective and safe for the treatment of nonunion of long bones regardless the stabilization method used.
Degree
thesis:*- Grantor
- Programa de Pós-graduação em Ciências Médicas
- Year dc:date.issued
- 2010
Author and committee
dc:creator, dc:contributor.*- Author dc:creator
-
- Bastos Filho, Ricardo Pinheiro dos Santos
Subjects
dc:subject × 14Rights
dc:rights- Statement dc:rights
-
- Acesso Aberto
- Language dc:language
- por
Identifiers
dc:identifier.*- Repository record dc:identifier.uri
- https://app.uff.br/riuff/handle/1/19052
- OAI identifier oai:identifier
- oai:app.uff.br:1/19052