Preliminary investigation on optical cavity-based biosensor using double-sided tape.

Early detection is the key to improving survival rates of diseases like cancer. Biosensors and microfluidics can aid in making detection more affordable and accessible. Our team has developed a foundational optical cavity-based biosensor capable of biomarker detection using low-cost fabrication methods, components, and a differential detection method. This biosensor laid the foundation for the creation of a double-sided tape-based biosensor to make fabrication three times faster and 96% cheaper. Double-sided tape defines and bonds the microfluidic channel to maintain a controlled fluid flow without leaking. It can also be used to actively control the cavity width using pulse width modulation (PWM)-based actuation. Cavity width adjustment was demonstrated through beam profile movement (maximum 1.44 mm), optical resonance, and by reducing the time required to achieve the optimal cavity width region (2.6-minute average). Overall, the simulations and data show this cavity structure with double-sided tape is worth further optimization and testing.

Name thesis:degree_name

M.S.E.C.E.

Level thesis:degree_level

Masters

Grantor

Baylor University.

Year dc:date.issued

2023

Author dc:creator

• Smith, Savanah, 2000-

Advisor dc:contributor.advisor

• Kim, Seunghyun (Professor of electrical and computer engineering)

• Optics.
• Biosensor.
• Microfluidics.
• Microfabrication.
• Double-sided tape.

Statement dc:rights

• Baylor University works are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. Contact libraryquestions@baylor.edu for inquiries about permission.

Language dc:language.iso

en

Handle dc:identifier.uri

https://hdl.handle.net/2104/12882

OAI identifier oai:identifier

oai:baylor-ir.tdl.org:2104/12882