The impact of multiple acute turkesterone doses on indirect hypertrophy and metabolic measures : a preliminary investigation.

Turkesterone is a naturally occurring plant steroid touted for its medicinal, pharmacological, and biological properties with no reported adverse side effects compared to traditional anabolic androgenic steroids. However, this ostensible enhancement to increase muscle protein synthesis (MPS) remains hitherto undescribed. To investigate whether turkesterone enhances insulin like growth factor 1 (IGF-1) and resting metabolic rate (RMR), eleven apparently healthy males volunteered to participate in the present study with samples collected pre-, 3H post-, and 24H post-ingestion. The aforementioned dependent variables were assessed using separate two-way (condition x time) mixed model ANOVAs with repeated measures (α=0.05). Analyses failed to reveal any significant main condition, time, or interaction main effects for serum IGF-1, RMR, lipid, and carbohydrate metabolism. Although non-significant serum IGF-1 concentrations increased with both turkesterone conditions and remained elevated when compared to placebo. Similarly, RMR remained elevated above baseline across the 3 hours assessed. Although these data fail to fully support turkesterone as a potent anabolic supplement, nevertheless, our findings are foundational to persistently tease apart this supplements purported ergogenic effects. Future investigations should, therein, aim to assess turkesterone-mediated IGF-1 increases on long-term whole-muscle growth across several training sessions to further substantiate its efficacy on anabolism when considering the significant gaps in the literature.

Name thesis:degree_name

M.S.

Level thesis:degree_level

Masters

Grantor

Baylor University.

Year dc:date.issued

2023

Author dc:creator

• Harris, Dillon R., 1998-

Advisor dc:contributor.advisor

• Funderburk, LesLee K.

• Turkesterone supplementation.
• Phytoecdysteroid.
• Ergogenic aid.
• Insulin-like growth factor-1 (IGF)
• Resting metabolic rate (RMR)

Statement dc:rights

• Baylor University works are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. Contact libraryquestions@baylor.edu for inquiries about permission.

Language dc:language.iso

en

Handle dc:identifier.uri

https://hdl.handle.net/2104/12793

OAI identifier oai:identifier

oai:baylor-ir.tdl.org:2104/12793