{"id":{"repo_id":"auckland-tech","oai_identifier":"oai:openrepository.aut.ac.nz:10292/17696"},"canonical_url":"https://search.dev.ndltd.org/etd/auckland-tech/oai:openrepository.aut.ac.nz:10292/17696","repository":{"repo_id":"auckland-tech","name":"AUT University","base_url":"https://openrepository.aut.ac.nz/server/oai/request"},"display":{"title":"COVID-19 Testing and Diagnosis in Children Under Six Years of Age: A Systematic Review","abstract":"Introduction: Severe acute respiratory syndrome was first detected in 2003 and escalated in 2019 with COVID-19 causing a worldwide pandemic. This new virus presented challenges in diagnosis, especially in those under 6 years of age. While often classified as a mild disease in children, COVID-19 still presents significant health risks in the young, especially for children under 1 year of age and those with pre-existing comorbidities. Because of this, clinical guidelines and protocols addressing COVID-19 testing in preschool- aged children became necessary to direct evidence-based practice. Aim: The aim of this systematic review was to explore COVID-19 testing and diagnosis in children under 6 years of age from international peer-reviewed published manuscripts to facilitate a wider and more thorough understanding of this practice from a diverse sample of parents, children, and health care providers to inform and direct practice within Aotearoa/New Zealand. Methods: A systematic review was undertaken based on guidelines by Siddaway et al. (2019). Extant empirical research published in peer-reviewed journals from 2020–2024 on COVID-19 testing in children under 6 years of age was identified from Scopus, CINAHL, MEDLINE via PubMed, and PsycInfo via Ovid databases. Data were analysed using deductive thematic analysis. Findings: Fourteen studies involving over 5,000 participants were included. Deductive content analysis identified seven key areas: 1. Symptomology, 2. Diagnostic tests, 4. Efficacy and acceptability of testing, 4. Viral loads, 5. Vulnerability/Risk factors, 6. Health outcomes, and 7. Recommendations. Conclusion: While common symptoms such as fever and cough are prevalent in children under 6 years of age infected with COVID-19, symptomology alone is not a foolproof diagnostic tool. Additional diagnostic testing, such as nasopharyngeal swabs and polymerase chain reaction testing, is complementary to diagnosis. However, an understanding of the risk factors for contracting COVID-19, as well as the vulnerability and health outcomes of children with COVID-19, is important to consider. Implications for practice: Common symptomology for children under 6 years of age includes fever and cough; however, these symptoms are also common for other viruses. A history of exposure to COVID-19 is the most frequent positive predictive factor for infection. An assessment of the child before any decisions on diagnostic testing is useful.","abstract_html":"Introduction: Severe acute respiratory syndrome was first detected in 2003 and escalated in 2019 with COVID-19 causing a worldwide pandemic. This new virus presented challenges in diagnosis, especially in those under 6 years of age. While often classified as a mild disease in children, COVID-19 still presents significant health risks in the young, especially for children under 1 year of age and those with pre-existing comorbidities. Because of this, clinical guidelines and protocols addressing COVID-19 testing in preschool- aged children became necessary to direct evidence-based practice. Aim: The aim of this systematic review was to explore COVID-19 testing and diagnosis in children under 6 years of age from international peer-reviewed published manuscripts to facilitate a wider and more thorough understanding of this practice from a diverse sample of parents, children, and health care providers to inform and direct practice within Aotearoa/New Zealand. Methods: A systematic review was undertaken based on guidelines by Siddaway et al. (2019). Extant empirical research published in peer-reviewed journals from 2020–2024 on COVID-19 testing in children under 6 years of age was identified from Scopus, CINAHL, MEDLINE via PubMed, and PsycInfo via Ovid databases. Data were analysed using deductive thematic analysis. Findings: Fourteen studies involving over 5,000 participants were included. Deductive content analysis identified seven key areas: 1. Symptomology, 2. Diagnostic tests, 4. Efficacy and acceptability of testing, 4. Viral loads, 5. Vulnerability/Risk factors, 6. Health outcomes, and 7. Recommendations. Conclusion: While common symptoms such as fever and cough are prevalent in children under 6 years of age infected with COVID-19, symptomology alone is not a foolproof diagnostic tool. Additional diagnostic testing, such as nasopharyngeal swabs and polymerase chain reaction testing, is complementary to diagnosis. However, an understanding of the risk factors for contracting COVID-19, as well as the vulnerability and health outcomes of children with COVID-19, is important to consider. Implications for practice: Common symptomology for children under 6 years of age includes fever and cough; however, these symptoms are also common for other viruses. A history of exposure to COVID-19 is the most frequent positive predictive factor for infection. An assessment of the child before any decisions on diagnostic testing is useful.","abstract_has_math":false,"creators":["Ure, Kirsty"],"institution":null,"degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":null,"school":null,"contributors":[],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2024,"date_issued":"2024","date_published":"2024","updated_at":"2026-07-27T18:45:57Z","subjects":[],"languages":[],"rights":[],"rights_urls":[],"identifier_entries":[{"key":"dc:identifier","label":"Identifier","values":["hdl:10292/17696"],"render_values":[{"text":"hdl:10292/17696","href":null,"code":true}]}]},"links":{"outbound_url":null,"outbound_label":null,"outbound_source":null},"metadata_groups":[{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.issued","label":"Date","values":["2024"]},{"key":"dc:type","label":"Dc Type","values":["Thesis"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["hdl:10292/17696"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.other","label":"Dc Description Other","values":["Introduction: Severe acute respiratory syndrome was first detected in 2003 and escalated in 2019 with COVID-19 causing a worldwide pandemic. This new virus presented challenges in diagnosis, especially in those under 6 years of age. While often classified as a mild disease in children, COVID-19 still presents significant health risks in the young, especially for children under 1 year of age and those with pre-existing comorbidities. Because of this, clinical guidelines and protocols addressing COVID-19 testing in preschool- aged children became necessary to direct evidence-based practice. Aim: The aim of this systematic review was to explore COVID-19 testing and diagnosis in children under 6 years of age from international peer-reviewed published manuscripts to facilitate a wider and more thorough understanding of this practice from a diverse sample of parents, children, and health care providers to inform and direct practice within Aotearoa/New Zealand. Methods: A systematic review was undertaken based on guidelines by Siddaway et al. (2019). Extant empirical research published in peer-reviewed journals from 2020–2024 on COVID-19 testing in children under 6 years of age was identified from Scopus, CINAHL, MEDLINE via PubMed, and PsycInfo via Ovid databases. Data were analysed using deductive thematic analysis. Findings: Fourteen studies involving over 5,000 participants were included. Deductive content analysis identified seven key areas: 1. Symptomology, 2. Diagnostic tests, 4. Efficacy and acceptability of testing, 4. Viral loads, 5. Vulnerability/Risk factors, 6. Health outcomes, and 7. Recommendations. Conclusion: While common symptoms such as fever and cough are prevalent in children under 6 years of age infected with COVID-19, symptomology alone is not a foolproof diagnostic tool. Additional diagnostic testing, such as nasopharyngeal swabs and polymerase chain reaction testing, is complementary to diagnosis. However, an understanding of the risk factors for contracting COVID-19, as well as the vulnerability and health outcomes of children with COVID-19, is important to consider. Implications for practice: Common symptomology for children under 6 years of age includes fever and cough; however, these symptoms are also common for other viruses. A history of exposure to COVID-19 is the most frequent positive predictive factor for infection. An assessment of the child before any decisions on diagnostic testing is useful."]},{"key":"dc:title","label":"Title","values":["COVID-19 Testing and Diagnosis in Children Under Six Years of Age: A Systematic Review"]}]}],"canonical_facts":{"dc:date.issued":["2024"],"dc:description.other":["Introduction: Severe acute respiratory syndrome was first detected in 2003 and escalated in 2019 with COVID-19 causing a worldwide pandemic. This new virus presented challenges in diagnosis, especially in those under 6 years of age. While often classified as a mild disease in children, COVID-19 still presents significant health risks in the young, especially for children under 1 year of age and those with pre-existing comorbidities. Because of this, clinical guidelines and protocols addressing COVID-19 testing in preschool- aged children became necessary to direct evidence-based practice. Aim: The aim of this systematic review was to explore COVID-19 testing and diagnosis in children under 6 years of age from international peer-reviewed published manuscripts to facilitate a wider and more thorough understanding of this practice from a diverse sample of parents, children, and health care providers to inform and direct practice within Aotearoa/New Zealand. Methods: A systematic review was undertaken based on guidelines by Siddaway et al. (2019). Extant empirical research published in peer-reviewed journals from 2020–2024 on COVID-19 testing in children under 6 years of age was identified from Scopus, CINAHL, MEDLINE via PubMed, and PsycInfo via Ovid databases. Data were analysed using deductive thematic analysis. Findings: Fourteen studies involving over 5,000 participants were included. Deductive content analysis identified seven key areas: 1. Symptomology, 2. Diagnostic tests, 4. Efficacy and acceptability of testing, 4. Viral loads, 5. Vulnerability/Risk factors, 6. Health outcomes, and 7. Recommendations. Conclusion: While common symptoms such as fever and cough are prevalent in children under 6 years of age infected with COVID-19, symptomology alone is not a foolproof diagnostic tool. Additional diagnostic testing, such as nasopharyngeal swabs and polymerase chain reaction testing, is complementary to diagnosis. However, an understanding of the risk factors for contracting COVID-19, as well as the vulnerability and health outcomes of children with COVID-19, is important to consider. Implications for practice: Common symptomology for children under 6 years of age includes fever and cough; however, these symptoms are also common for other viruses. A history of exposure to COVID-19 is the most frequent positive predictive factor for infection. An assessment of the child before any decisions on diagnostic testing is useful."],"dc:identifier":["hdl:10292/17696"],"dc:title":["COVID-19 Testing and Diagnosis in Children Under Six Years of Age: A Systematic Review"],"dc:type":["Thesis"]},"updated_at":"2026-07-27T18:45:57Z"}