{"id":{"repo_id":"auckland-ms","oai_identifier":"oai:researchspace.auckland.ac.nz:2292/41776"},"canonical_url":"https://search.dev.ndltd.org/etd/auckland-ms/oai:researchspace.auckland.ac.nz:2292/41776","repository":{"repo_id":"auckland-ms","name":"University of Auckland","base_url":"https://researchspace.auckland.ac.nz/server/oai/request"},"display":{"title":"The role of muscle and circulatory microRNAs as regulators and biomarkers of muscle function","abstract":"Skeletal muscle is an abundant tissue type with critical roles in locomotion, force production and whole body energy regulation. Skeletal muscle mass and function are adaptively regulated by multiple stimuli including physical loading (exercise), nutrient intake (protein supplementation) and lifestyle events (injury and unloading). MicroRNAs (miRNAs) are short non-coding RNAs with the capacity to target specific mRNAs for breakdown and thereby alter the rate and extent of protein expression. 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