The purpose of this study was to measure hormonal and metabolic markers in humans to see if simulating dehydration would emulate measures that are seen in prediabetic humans. 60 volunteers were divided into equal categories by sex and body mass index of normal or overweight. Participants completed two oral glucose tolerance tests (OGTT) after being intravenously infused with a isotonic or hypertonic saline solution for 120 minutes in a counter balanced order. All trials began with a euhydrated subject with a urine specific gravity (USG)
","abstract_html":"<p>The purpose of this study was to measure hormonal and metabolic markers in humans to see if simulating dehydration would emulate measures that are seen in prediabetic humans. 60 volunteers were divided into equal categories by sex and body mass index of normal or overweight. Participants completed two oral glucose tolerance tests (OGTT) after being intravenously infused with a isotonic or hypertonic saline solution for 120 minutes in a counter balanced order. All trials began with a euhydrated subject with a urine specific gravity (USG)</p>","abstract_has_math":false,"creators":["Lewis, Zachary Robert"],"institution":null,"degree_name":"Master of Science in Kinesiology (MS)","degree_level":"Thesis","degree_discipline":null,"degree_department":null,"school":null,"contributors":["Greene, Nicholas P.","McDermott, Brendon P."],"advisors":["Kavouras, Stavros A."],"committee_chairs":[],"committee_members":[],"year":2018,"date_issued":"2018-12-01T08:00:00Z","date_published":"2018-12-01T08:00:00Z","updated_at":"2026-07-24T00:58:44Z","subjects":["Dehydration","Glucose","Hydration","Metabolism","Endocrinology, Diabetes, and Metabolism","Other Kinesiology"],"languages":[],"rights":[],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"https://scholarworks.uark.edu/etd/3001","outbound_label":"Repository record","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Greene, Nicholas P.","McDermott, Brendon P."]},{"key":"dc:contributor.advisor","label":"Advisor","values":["Kavouras, Stavros A."]},{"key":"dc:creator","label":"Author","values":["Lewis, Zachary Robert"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date","label":"Dc Date","values":["2018"]},{"key":"dc:date.available","label":"Dc Date Available","values":["2020-12-03T08:00:00Z"]},{"key":"thesis:degree_level","label":"Degree Level","values":["Thesis"]},{"key":"thesis:degree_name","label":"Degree Name","values":["Master of Science in Kinesiology (MS)"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Dehydration","Glucose","Hydration","Metabolism","Endocrinology, Diabetes, and Metabolism","Other Kinesiology"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["https://scholarworks.uark.edu/etd/3001"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["The purpose of this study was to measure hormonal and metabolic markers in humans to see if simulating dehydration would emulate measures that are seen in prediabetic humans. 60 volunteers were divided into equal categories by sex and body mass index of normal or overweight. Participants completed two oral glucose tolerance tests (OGTT) after being intravenously infused with a isotonic or hypertonic saline solution for 120 minutes in a counter balanced order. All trials began with a euhydrated subject with a urine specific gravity (USG)
"]},{"key":"dc:title","label":"Title","values":["The Effect of Dehydration on Metabolism and Energy Substrate Utilization"]}]}],"canonical_facts":{"dc:contributor":["Greene, Nicholas P.","McDermott, Brendon P."],"dc:contributor.advisor":["Kavouras, Stavros A."],"dc:creator":["Lewis, Zachary Robert"],"dc:date":["2018"],"dc:date.available":["2020-12-03T08:00:00Z"],"dc:description.abstract":["The purpose of this study was to measure hormonal and metabolic markers in humans to see if simulating dehydration would emulate measures that are seen in prediabetic humans. 60 volunteers were divided into equal categories by sex and body mass index of normal or overweight. Participants completed two oral glucose tolerance tests (OGTT) after being intravenously infused with a isotonic or hypertonic saline solution for 120 minutes in a counter balanced order. All trials began with a euhydrated subject with a urine specific gravity (USG)
"],"dc:identifier":["https://scholarworks.uark.edu/etd/3001"],"dc:subject":["Dehydration","Glucose","Hydration","Metabolism","Endocrinology, Diabetes, and Metabolism","Other Kinesiology"],"dc:title":["The Effect of Dehydration on Metabolism and Energy Substrate Utilization"],"thesis:degree_level":["Thesis"],"thesis:degree_name":["Master of Science in Kinesiology (MS)"]},"updated_at":"2026-07-24T00:58:44Z"}