The Osseointegration of Magnesium Oxidized Implant

BACKGROUND & OBJECTIVE: Osseointegrated implants have proven to be successful in both full and partial edentulous patients since the 1960s. Titanium implants have a thin oxide surface layer and the properties of this layer may explain the good biocompatibility. Recently, anodization of the implant surface is on the rise as a way to improve the osseointegration. The aim of this study is to compare the osseointegration between magnesium oxidized implant, TiUnite and machine-turned implant, to establish a better understanding of the effect of anodic oxidization on commercially pure titanium. METHODS: 3 Mini pigs (24 months) were chosen and from 1st premolar to 2nd molar of the mandible were carefully extracted on each side. 2 months later, total 27 implants (9 of each type, 3.3×7 mm) were inserted. Implant stability was estimated by RFA (Resonance frequency analysis) method in installation to 2, 4 & 6 weeks. Statistical analyses of RFA values were performed with time and between groups using repeated measure ANOVA and turkey's multiple comparison test. After healing time of 6 weeks, the bone specimens were subjected to histomorphometric analysis and statistical analysis was performed using Kruskal-Wallis test by SPSS program of the each measured BIC (bone to implant contact) and BA(bone amount) value. Differences were considered statistically significant at p＜0.05 and not significant at p＞0.05. RESULTS: In analyzing the mean RFA value for the observation periods, three types of implants yielded a slight decrease after 2 weeks, followed by increase at 4 ∼ 6 weeks. Magnesium oxidized implants demonstrated significantly higher RFA mean value at 6 weeks comparing other groups. The differences of RFA values with time and between groups were statistically significant. In examining the mean BIC value of the 3 implants after 6 weeks of healing time, magnesium oxidized implant and TiUnite demonstrated significantly higher than machine-turned implant (p＜ 0.05, respectively), and there was no difference between them. Compared to machine-turned implant, magnesium oxidized implant showed a significant mean BA value (p = 0.046), whereas TiUnite showed no significant difference (p＞ 0.05). CONCLUSION: Within limits of this study, it can be concluded that magnesium oxidized implant may reduce high failure rates in the postimplantation stage and in compromised bone. Moreover, it is possible to shorten bone healing time from surgery to functional loading, and to enhance the possibility of immediate / early loading. Later, it is necessary for further study.

Author dc:creator

• 배, 상범

Contributors dc:contributor

• 송, 승일
• 대학원 의학과
• 200724373

• 임플란트 표면
• 마그네슘 양극산화 임플란트
• 조직형태학적 분석
• 공명진동수 분석
• Osseointegration
• Magnesium Oxidized Implant

Language dc:language

ko

Identifier

http://dcoll.ajou.ac.kr:9080/dcollection/jsp/common/DcLoOrgPer.jsp?sItemId=000000011803
000000011803

OAI identifier oai:identifier

oai:repository.ajou.ac.kr:201003/4396