Risk Factors for Acute Prostatitis after Transrectal Biopsy of the Prostate

PURPOSE: We investigate the incidence, clinical features, pathogenic bacteria and risk factors associated with acute prostatitis after transrectal prostate biopsy. MATERIALS AND METHODS: We retrospectively reviewed the medical records of 923 transrectal ultrasound-guided needle biopsy of the prostate on 878 patients performed in our institution from June 2004 to May 2009. The indications for transrectal prostate biopsy were generally serum prostate-specific antigen (PSA) elevation and/or abnormal findings on digital rectal examination. All biopsies were performed with the patient hospitalized except for 10 patients who refused to be hospitalized, and ciprofloxacin was administered as antibiotic prophylaxis. The incidence, clinical features, pathogenic bacteria and potential risk factors associated with acute prostatitis after prostate biopsy were evaluated. RESULTS: Acute prostatitis developed in 18 (2.0%) cases after transrectal prostate biopsy. Among them, 9 (1.0%) had bacteremia and 2 (0.2%) showed clinical features of sepsis. Of the total 50 urine or blood specimens sent for culture study, 27 (54.0%) specimens showed positive cultures, including E. coli in 25. Among 27 culture positive specimens, 26 (96.3%) were resistant to ciprofloxacin. Among the potential risk factors for acute prostatitis after prostate biopsy, biopsy performed as an outpatient procedure without cleansing enema (p=0.001) and past history of cerebrovascular accident (p=0.048) were statistically significant. CONCLUSIONS: Fluoroquinolone is effective as antibiotic prophylaxis for transrectal prostate biopsy in the majority of cases. The incidence of acute prostatitis after transrectal prostate biopsy was 2.0% and almost all were caused by fluoroquinolone-resistant E. coli. Cleansing enema is recommended before transrectal prostate biopsy.

Author dc:creator

• 김, 상진

Contributors dc:contributor

• 김, 세중
• 대학원 의학과
• 200924230

• Biopsy
• Prostate
• Prostatitis
• Risk Factors
• 경직장전립선생검
• 급성전립선염

Language dc:language

en

Identifier

http://dcoll.ajou.ac.kr:9080/dcollection/jsp/common/DcLoOrgPer.jsp?sItemId=000000011470
000000011470

OAI identifier oai:identifier

oai:repository.ajou.ac.kr:201003/4362