{"id":{"repo_id":"ajou","oai_identifier":"oai:repository.ajou.ac.kr:201003/4314"},"canonical_url":"https://search.dev.ndltd.org/etd/ajou/oai:repository.ajou.ac.kr:201003/4314","repository":{"repo_id":"ajou","name":"Ajou University","base_url":"http://repository.ajou.ac.kr/oai/request"},"display":{"title":"Prognostic Factors in Transitional Cell Carcinoma of Upper Urinary Tract after Radical Nephroureterectomy","abstract":"Purpose : The aim of this study was to evaluate the prognostic factors for survival in patients treated surgically for transitional cell carcinoma of the upper urinary tract (UUT-TCC). Materials and Methods : I retrospectively reviewed the medical records of 87 patients (64 men and 23 women, mean age of 62.2 years) with UUT-TCC who had undergone radical nephroureterectomy at our institution between June 1994 and June 2009. The median follow-up period was 32 months. The prognostic significance of various clinicopathological variables for recurrence-free and cancer-specific survival was analyzed using univariate and multivariate analysis. Results : Of total 87 patients, 21 patients (24.1%) developed local recurrence or distant metastasis and 16 patients (18.4%) died during the follow-up period. The 5-year recurrence-free and cancer-specific survival rates were 74.6% and 75.2%, respectively. On univariate analysis, hydronephrosis, T stage, N stage, and lymphovascular invasion (LVI) were significant prognostic factors for recurrence-free and cancer-specific survival. On multivariate analysis, T stage and LVI were independent prognostic factors for recurrence-free and cancer-specific survival. Conclusions : The T stage and LVI are independent prognostic factors for recurrence-free and cancer-specific survival in patients with UUT-TCC treated by radical nephroureterectomy. These findings would be helpful for guiding the decisions about adjuvant therapies and surveillance interval.","abstract_html":"Purpose : The aim of this study was to evaluate the prognostic factors for survival in patients treated surgically for transitional cell carcinoma of the upper urinary tract (UUT-TCC). Materials and Methods : I retrospectively reviewed the medical records of 87 patients (64 men and 23 women, mean age of 62.2 years) with UUT-TCC who had undergone radical nephroureterectomy at our institution between June 1994 and June 2009. The median follow-up period was 32 months. The prognostic significance of various clinicopathological variables for recurrence-free and cancer-specific survival was analyzed using univariate and multivariate analysis. Results : Of total 87 patients, 21 patients (24.1%) developed local recurrence or distant metastasis and 16 patients (18.4%) died during the follow-up period. The 5-year recurrence-free and cancer-specific survival rates were 74.6% and 75.2%, respectively. On univariate analysis, hydronephrosis, T stage, N stage, and lymphovascular invasion (LVI) were significant prognostic factors for recurrence-free and cancer-specific survival. On multivariate analysis, T stage and LVI were independent prognostic factors for recurrence-free and cancer-specific survival. Conclusions : The T stage and LVI are independent prognostic factors for recurrence-free and cancer-specific survival in patients with UUT-TCC treated by radical nephroureterectomy. These findings would be helpful for guiding the decisions about adjuvant therapies and surveillance interval.","abstract_has_math":false,"creators":["김, 영균"],"institution":null,"degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":null,"school":null,"contributors":["김, 세중","대학원 의학과","104846"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2011,"date_issued":"2011-10-28T06:16:15Z","date_published":"2011-10-28T06:16:15Z","updated_at":"2026-07-24T00:51:34Z","subjects":["Urinary Tract Cancer","Transitional Cell Carcinoma","Prognosis","예후인자","상부요로이행세포암","근치적 신요관적출술"],"languages":["en"],"rights":[],"rights_urls":[],"identifier_entries":[{"key":"dc:identifier","label":"Identifier","values":["http://dcoll.ajou.ac.kr:9080/dcollection/jsp/common/DcLoOrgPer.jsp?sItemId=000000011184","000000011184"],"render_values":[{"text":"http://dcoll.ajou.ac.kr:9080/dcollection/jsp/common/DcLoOrgPer.jsp?sItemId=000000011184","href":"http://dcoll.ajou.ac.kr:9080/dcollection/jsp/common/DcLoOrgPer.jsp?sItemId=000000011184","code":true},{"text":"000000011184","href":null,"code":true}]}]},"links":{"outbound_url":"http://repository.ajou.ac.kr/handle/201003/4314","outbound_label":"Repository record","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["김, 세중","대학원 의학과","104846","김, 영균"]},{"key":"dc:creator","label":"Author","values":["김, 영균"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date","label":"Dc Date","values":["2011-10-28T06:16:15Z","2011"]},{"key":"dc:type","label":"Dc Type","values":["Thesis","Theses"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Urinary Tract Cancer","Transitional Cell Carcinoma","Prognosis","예후인자","상부요로이행세포암","근치적 신요관적출술"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language","label":"Dc Language","values":["en"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["http://repository.ajou.ac.kr/handle/201003/4314","http://dcoll.ajou.ac.kr:9080/dcollection/jsp/common/DcLoOrgPer.jsp?sItemId=000000011184","000000011184"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["Purpose : The aim of this study was to evaluate the prognostic factors for survival in patients treated surgically for transitional cell carcinoma of the upper urinary tract (UUT-TCC). Materials and Methods : I retrospectively reviewed the medical records of 87 patients (64 men and 23 women, mean age of 62.2 years) with UUT-TCC who had undergone radical nephroureterectomy at our institution between June 1994 and June 2009. The median follow-up period was 32 months. The prognostic significance of various clinicopathological variables for recurrence-free and cancer-specific survival was analyzed using univariate and multivariate analysis. Results : Of total 87 patients, 21 patients (24.1%) developed local recurrence or distant metastasis and 16 patients (18.4%) died during the follow-up period. The 5-year recurrence-free and cancer-specific survival rates were 74.6% and 75.2%, respectively. On univariate analysis, hydronephrosis, T stage, N stage, and lymphovascular invasion (LVI) were significant prognostic factors for recurrence-free and cancer-specific survival. On multivariate analysis, T stage and LVI were independent prognostic factors for recurrence-free and cancer-specific survival. Conclusions : The T stage and LVI are independent prognostic factors for recurrence-free and cancer-specific survival in patients with UUT-TCC treated by radical nephroureterectomy. These findings would be helpful for guiding the decisions about adjuvant therapies and surveillance interval.","ABSTRACT ⅰ TABLE OF CONTENTS ⅲ LIST OF TABLES iv Ⅰ. INTRODUCTION 1 Ⅱ. MATERIALS AND METHODS 2 Ⅲ. RESULTS 4 Ⅳ. DISCUSSION 9 Ⅴ. CONCLUSION 14 REFERENCES 15 국문요약 19","Master"]},{"key":"dc:title","label":"Title","values":["Prognostic Factors in Transitional Cell Carcinoma of Upper Urinary Tract after Radical Nephroureterectomy","근치적 신요관전적출술을 시행받은 상부요로 이행세포암에서 예후인자"]}]}],"canonical_facts":{"dc:contributor":["김, 세중","대학원 의학과","104846","김, 영균"],"dc:creator":["김, 영균"],"dc:date":["2011-10-28T06:16:15Z","2011"],"dc:description":["Purpose : The aim of this study was to evaluate the prognostic factors for survival in patients treated surgically for transitional cell carcinoma of the upper urinary tract (UUT-TCC). Materials and Methods : I retrospectively reviewed the medical records of 87 patients (64 men and 23 women, mean age of 62.2 years) with UUT-TCC who had undergone radical nephroureterectomy at our institution between June 1994 and June 2009. The median follow-up period was 32 months. The prognostic significance of various clinicopathological variables for recurrence-free and cancer-specific survival was analyzed using univariate and multivariate analysis. Results : Of total 87 patients, 21 patients (24.1%) developed local recurrence or distant metastasis and 16 patients (18.4%) died during the follow-up period. The 5-year recurrence-free and cancer-specific survival rates were 74.6% and 75.2%, respectively. On univariate analysis, hydronephrosis, T stage, N stage, and lymphovascular invasion (LVI) were significant prognostic factors for recurrence-free and cancer-specific survival. On multivariate analysis, T stage and LVI were independent prognostic factors for recurrence-free and cancer-specific survival. Conclusions : The T stage and LVI are independent prognostic factors for recurrence-free and cancer-specific survival in patients with UUT-TCC treated by radical nephroureterectomy. These findings would be helpful for guiding the decisions about adjuvant therapies and surveillance interval.","ABSTRACT ⅰ TABLE OF CONTENTS ⅲ LIST OF TABLES iv Ⅰ. INTRODUCTION 1 Ⅱ. MATERIALS AND METHODS 2 Ⅲ. RESULTS 4 Ⅳ. DISCUSSION 9 Ⅴ. CONCLUSION 14 REFERENCES 15 국문요약 19","Master"],"dc:identifier":["http://repository.ajou.ac.kr/handle/201003/4314","http://dcoll.ajou.ac.kr:9080/dcollection/jsp/common/DcLoOrgPer.jsp?sItemId=000000011184","000000011184"],"dc:language":["en"],"dc:subject":["Urinary Tract Cancer","Transitional Cell Carcinoma","Prognosis","예후인자","상부요로이행세포암","근치적 신요관적출술"],"dc:title":["Prognostic Factors in Transitional Cell Carcinoma of Upper Urinary Tract after Radical Nephroureterectomy","근치적 신요관전적출술을 시행받은 상부요로 이행세포암에서 예후인자"],"dc:type":["Thesis","Theses"]},"updated_at":"2026-07-24T00:51:34Z"}