The Evaluation of Usefulness of the FEA and Relationship Between Trabecular Microstructural and Biomechanical Properties In Human Femoral Head

To evaluate the usefulness of the finite element analysis(FEA) and the relationship between trabecular bone microstructure and its biomechanical properties, the microimage-based FEA and the experimental test were performed in the same bone cores from the primary compressive trabecular system of human femoral head. Twenty-one human femoral heads were obtained from 11 patients undergoing total hip arthroplasty and 10 cadavers at Ajou University Hospital. Cylindrical trabecular bone were cored from the primary compressive trabecular system of the femoral head. The sample size was diameter of 19 ㎜, height of 15 ㎜. All samples were scanned with a high-resolution micro-computed tomography system at a spatial resolution of 21.31 ㎛. Based on the serial micro-CT images, a volume of interest (VOI) was selected to be 9.50 ㎜ of diameter and 7.50 ㎜ of side length. The morphometry indices were directly calculated from ANT software (Skyscan, Belgium). Based on these micro-images of trabecular bone, the finite element model was created, and the finite element analysis and the compressive test were performed respectively. The yield stress and Young's modulus were calculated from two test. The average yield stress and Young's modulus from FEA and Instron system were 13.04 ㎫ and 1.30 ㎬, 13.06 ㎫ and 0.11 ㎬, respectively. Pearson correlations between Of the morphometry indices, Tb.Th, Tb.Sp, S/V, BV/TV and Tb.N were significantly correlated with from FEA, while only BV/TV and Tb.N were significantly correlated with the yield stress and Young's modulus from Instron system. The correlations between the yield calculated from FEA and Instron were significant (r = 0.623), but not for the Young's modulus. The results showed a significant correlation between the trabecular microstructure and its biomechanical properties. It supports the concept that bone strength is not only depended on bone quantity, but also depended on bone quality. The biomechanical properties of trabecular bone calculated from FEA are well correlated with those from the mechanical test, suggesting that the micro-image-based finite element analysis as a substitute of the mechanical test can be a useful tool to predict the fracture risk.

Author dc:creator

• 백, 명현

Contributors dc:contributor

• 원, 예연
• 대학원 의학과
• 200424448

• 골소주군
• 미세구조
• 생역학적
• 태퇴골두
• 유한요소법

Language dc:language

ko

Identifier

http://dcoll.ajou.ac.kr:9080/dcollection/jsp/common/DcLoOrgPer.jsp?sItemId=000000002217
000000002217

OAI identifier oai:identifier

oai:repository.ajou.ac.kr:201003/1663