Cardiac Co-morbidities in Chronic Obstructive Pulmonary Disease

BACKGROUND: Coronary artery disease (CAD) is a frequent co-morbidity in chronic obstructive pulmonary disease (COPD) and cardiovascular disease is the most common cause of death in COPD. Therefore, this study was performed to identify the prognostic factors associated with the CAD in COPD and investigate the independent risk factors for mortality in COPD patients who underwent comprehensive cardiac evaluations METHODS: We retrospectively reviewed 405 patients with COPD who had undergone comprehensive cardiac evaluations including coronary angiography, coronary multi-detector computed tomography and echocardiography in Ajou University Hospital from Jan 2000 to Dec 2012. Survival analyses of prognostic factors were performed in this retrospective cohort. RESULTS: Male gender, hypertension, left heart failure, lower hemoglobin level, and lower serum HDL were independently associated with the presence of CAD in COPD (p<0.05). Older age, lower body mass index(BMI), lower left ventricular ejection fraction, lower forced expiratory volume in one second(FEV1), and lower hemoglobin level were independently associated with higher mortality in total COPD group (p<0.05), whereas presence of CAD was not. CONCLUSION: Our study identified lower left ventricular ejection fraction and lower hemoglobin level along with older age, lower BMI, and lower FEV1 as independent risk factors for the mortality of COPD patients, suggesting that multidisciplinary approaches are required in the care of COPD patients. Male gender, hypertension, left heart failure, and lower serum HDL level were independent predictors for the presence of CAD in COPD.

Author dc:creator

• 안, 영환

Contributors dc:contributor

• 박, 주헌
• 대학원 의학과
• 201324365

• Chronic obstructive pulmonary disease(COPD)
• coronary artery disease
• mortalith
• 만성폐쇄성폐질환
• 관상동맥질환
• 사망률

Language dc:language

en

Identifier

http://dcoll.ajou.ac.kr:9080/dcollection/jsp/common/DcLoOrgPer.jsp?sItemId=000000020130
000000020130

OAI identifier oai:identifier

oai:repository.ajou.ac.kr:201003/11875