{"id":{"repo_id":"adelaide","oai_identifier":"oai:digital.library.adelaide.edu.au:2440/150404"},"canonical_url":"https://search.dev.ndltd.org/etd/adelaide/oai:digital.library.adelaide.edu.au:2440/150404","repository":{"repo_id":"adelaide","name":"University of Adelaide","base_url":"https://digital.library.adelaide.edu.au/server/oai/request"},"display":{"title":"Designing Immune-Instructive Biomaterials: The Interplay of Biomaterial surface, IgG Unfolding, and Macrophage Modulation","abstract":"This doctoral research investigates how biomaterials can be designed to guide the immune system’s response in beneficial ways. By studying how the immune system interacts with different model implant materials, the work reveals strategies to modulate immune response, promote healing and improve the integration of medical implants. These findings contribute to the development of smarter biomaterials that work in harmony with the body’s natural defences, offering new possibilities for regenerative medicine and immune modulation.","abstract_html":"This doctoral research investigates how biomaterials can be designed to guide the immune system’s response in beneficial ways. By studying how the immune system interacts with different model implant materials, the work reveals strategies to modulate immune response, promote healing and improve the integration of medical implants. These findings contribute to the development of smarter biomaterials that work in harmony with the body’s natural defences, offering new possibilities for regenerative medicine and immune modulation.","abstract_has_math":false,"creators":["Alemie, Markos Negash"],"institution":"University of South Australia","degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":null,"school":null,"contributors":[],"advisors":["Diener, Kerrilyn"],"committee_chairs":[],"committee_members":[],"year":2025,"date_issued":"2025-12-11","date_published":"2025-12-11","updated_at":"2026-07-24T00:50:39Z","subjects":[],"languages":["en"],"rights":[],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"https://hdl.handle.net/2440/150404","outbound_label":"Handle","outbound_source":"dc:identifier.uri"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor.advisor","label":"Advisor","values":["Diener, Kerrilyn"]},{"key":"dc:creator","label":"Author","values":["Alemie, Markos Negash"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.issued","label":"Date","values":["2025-12-11"]},{"key":"dc:publisher","label":"Institution","values":["University of South Australia"]},{"key":"dc:type","label":"Dc Type","values":["Thesis"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language.iso","label":"Language (ISO)","values":["en"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier.uri","label":"Identifier URI","values":["https://hdl.handle.net/2440/150404"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["xx, 237 pages"]},{"key":"dc:description.abstract","label":"Abstract","values":["This doctoral research investigates how biomaterials can be designed to guide the immune system’s response in beneficial ways. By studying how the immune system interacts with different model implant materials, the work reveals strategies to modulate immune response, promote healing and improve the integration of medical implants. These findings contribute to the development of smarter biomaterials that work in harmony with the body’s natural defences, offering new possibilities for regenerative medicine and immune modulation."]},{"key":"dc:title","label":"Title","values":["Designing Immune-Instructive Biomaterials: The Interplay of Biomaterial surface, IgG Unfolding, and Macrophage Modulation"]}]}],"canonical_facts":{"dc:contributor.advisor":["Diener, Kerrilyn"],"dc:creator":["Alemie, Markos Negash"],"dc:date.issued":["2025-12-11"],"dc:description":["xx, 237 pages"],"dc:description.abstract":["This doctoral research investigates how biomaterials can be designed to guide the immune system’s response in beneficial ways. By studying how the immune system interacts with different model implant materials, the work reveals strategies to modulate immune response, promote healing and improve the integration of medical implants. These findings contribute to the development of smarter biomaterials that work in harmony with the body’s natural defences, offering new possibilities for regenerative medicine and immune modulation."],"dc:identifier.uri":["https://hdl.handle.net/2440/150404"],"dc:language.iso":["en"],"dc:publisher":["University of South Australia"],"dc:title":["Designing Immune-Instructive Biomaterials: The Interplay of Biomaterial surface, IgG Unfolding, and Macrophage Modulation"],"dc:type":["Thesis"]},"updated_at":"2026-07-24T00:50:39Z"}