Vergleichende Untersuchung zu Lebensgewohnheiten und Lebensumfeld von Patienten mit selbstberichteter Multipler Chemikaliensensitivität, Duftstoffallergien oder Polyposis nasi
Background: Environmental factors are discussed as possible causes and/or triggers of multiple chemical sensitivity (MCS), fragrance allergies (FA) and polyposis nasi (PN). Besides other organ systems, a joint effect organ of MCS, FA and PN is the respiratory tract. Therefore, aim of the present study was to characterize and compare living conditions and living factors of persons with self-reported MCS (sMCS), FA or PN.Material and Methods: Dependence of variable distribution of a standardized questionnaire of living conditions and living factors was compared between the three patient groups using Pearson’s X²-test. In case of a significant value, pairwise comparisons were done with Fisher’s exact test. Metric variables were compared with Kruskal-Wallis- and Mann-Whitney-U-test. Significant results in Fisher’s exact test or Mann-Whitney-U-test were Bonferroni adjusted.Results: The sMCS group consisted of 14 men and 45 women, the FA group of 19 men and 25 women and the PN group of 42 men and 27 women. Questionnaire variables with a significantly different distribution between the three patient groups were: Chemicals as suspected cause of health disturbances (p=0.000), use of perfume (p=0.000), present amalgam fillings (p=0.000), alcohol consumption (p=0.007), age of residential building (p=0.03), use of humidifier at home (p=0.014), mould exposure at home (p=0.035), age of furniture at home (p=0.001), indoor plants at home (p=0.029), use of disinfections (p=0.006) and insecticides (p=0.004), daily time stayed at home (p=0.032), different kinds of annoyance at home (p=0.000), sense of wellbeing at home (p=0.000) as well as exposures to photocopy machines (p=0.000) and odors (p=0.000) at workplace. In most cases, the questionnaire variables investigated were significantly different distributed between the sMCS group and the FA-/PN group.Conclusions: The different distribution of the questionnaire variables investigated between the sMCS-, FA- and PN group regarded mainly environmental factors with odorous components. Reactions to these factors were lesser pronounced in the FA group than in the sMCS group. In the PN group no association between PN and the living conditions and living factors investigated were observed.
info:eu-repo/classification/ddc/610, Umweltmedizin, Medizin, Duftstoffallergien, sMCS, Polyposis nasi, Lebensgewohnheiten, Lebensumfeld, self-reported multiple chemical sensitivity, fragrance allergies, living conditions, living factors
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