Charakterisierung der Lebensgewohnheiten und des Lebensumfeldes von Patienten mit selbstberichteter Multipler Chemikaliensensitivität (sMCS)
type: CreativeWork
description: Introduction: Multiple Chemical Sensitivity (MCS) is a syndrome with many speculations about etiology, risk factors and pathomechanism, but few scientifically consolidated findings. Therefore living conditions and living factors of persons with self-reported MCS (sMCS) in comparison to a control group of the same anthroposphere were systematically investigated. Research methods: In a case-control study patients with sMCS were investigated in comparison to a not MCS affected control group of the same anthroposphere. The sMCS group was characterized using the modified MCS-questionnaire from Hüppe et al. concerning symptom inducing substances. The data about living conditions and living factors was collected by a posted questionnaire all participants filled in personally. The dependence of questionnaire-obtained living conditions and living factors on sMCS and controls were analyzed with Pearson’s chi²-, Fisher’s exact- and Mann-Whitney-U-test. Results: The sMCS group consists of 59 persons concerned (14 men, 45 women, mean age: 48.4 ± 9.4 years), the control group of 40 persons (14 men, 26 women, mean age: 43.9 ± 9.0 years). The modified MCS-questionnaire from Hüppe et al. differentiated between the sMCS and control group with 91.8% sensitivity and 83.9% specifity. The observed differences in living conditions and living factors between cases and controls regarded mainly nutrition (e.g., more special nutrition habit of sMCS-affected persons), social area (e.g., more invalidity allowance of sMCS-affected persons), odorous annoyance (e.g., lesser use of universal cleaners by sMCS-affected persons) and dental prothesis (e.g., fewer amalgam fillings in sMCS-affected persons). Altogether, compared to the control group the sMCS-affected persons had worse social conditions and lower exposures, esp. to odorous factors. Conclusion: Exposures which might possibly be causative for MCS could not be observed. Even if an exogenous cause of MCS should not exist, a special susceptibi…
abstract: Introduction: Multiple Chemical Sensitivity (MCS) is a syndrome with many speculations about etiology, risk factors and pathomechanism, but few scientifically consolidated findings. Therefore living conditions and living factors of persons with self-reported MCS (sMCS) in comparison to a control group of the same anthroposphere were systematically investigated. Research methods: In a case-control study patients with sMCS were investigated in comparison to a not MCS affected control group of the same anthroposphere. The sMCS group was characterized using the modified MCS-questionnaire from Hüppe et al. concerning symptom inducing substances. The data about living conditions and living factors was collected by a posted questionnaire all participants filled in personally. The dependence of questionnaire-obtained living conditions and living factors on sMCS and controls were analyzed with Pearson’s chi²-, Fisher’s exact- and Mann-Whitney-U-test. Results: The sMCS group consists of 59 persons concerned (14 men, 45 women, mean age: 48.4 ± 9.4 years), the control group of 40 persons (14 men, 26 women, mean age: 43.9 ± 9.0 years). The modified MCS-questionnaire from Hüppe et al. differentiated between the sMCS and control group with 91.8% sensitivity and 83.9% specifity. The observed differences in living conditions and living factors between cases and controls regarded mainly nutrition (e.g., more special nutrition habit of sMCS-affected persons), social area (e.g., more invalidity allowance of sMCS-affected persons), odorous annoyance (e.g., lesser use of universal cleaners by sMCS-affected persons) and dental prothesis (e.g., fewer amalgam fillings in sMCS-affected persons). Altogether, compared to the control group the sMCS-affected persons had worse social conditions and lower exposures, esp. to odorous factors. Conclusion: Exposures which might possibly be causative for MCS could not be observed. Even if an exogenous cause of MCS should not exist, a special susceptibi…
author: Weißbach, Wibke
language: ger
keywords: info:eu-repo/classification/ddc/610, Medizin, Fragebogen, Exposition, Lebensgewohnheiten, Lebensumfeld, Multiple chemical sensitivity, living conditions, living factors
date published: 2006
date modified: 2026-07-30T19:43:10Z
provider: RWTH Aachen University
publisher: Networked Digital Library of Theses and Dissertations
type: WebPage
source organization: Publikationsserver der RWTH Aachen University