Chirurgie der extrahepatischen Gallenwegskarzinome
The carcinoma of the extrahepatic bile duct and gallbladder has with the exception of the carcinoma of the papilla of Vater a very bad prognosis. Even though resection rates and perioperative mortality were improved, the survival rates remain unfavourably. This study investigated retrospectively the survival and success of surgical therapy of 87 patients with carcinomas of the extrahepatic bile duct and gallbladder, which were treated at the surgical department of the university hospital of the RWTH Aachen, Germany, from 1986 until 1997. This data and the follow-up were obtained by retrieving information from the patient's files and through questioning of the patient's physicians. Additionally was the obtained data screened for a clinical or laboratory parameter which correlated with the survival rates. Results: The 1 year survival rates were 19% for the proximal bile duct carcinoma, 44% for the middle bile duct carcinoma, 44% for the distal bile duct carcinoma, 17% for the gallbladder carcinoma and 75% for the carcinoma of the papilla of Vater. The 5 year survival rates were for the proximal bile duct carcinoma 6%, for the middle and distal bile duct carcinoma 0%, for the gallbladder carcinoma 7% and for the carcinoma of the papilla of Vater 55%. No parameter, that correlated with the survival time, could be found. The resection rates with intend to cure showed a 22% resection rate for the proximal bile duct carcinoma, a 12,5% resection rate for the middle bile duct carcinoma, a 75% resection rate for the distal bile duct carcinoma, a 24% resection rate for the gallbladder carcinoma and an 83% resection rate for the carcinoma of the papilla of Vater. The perioperative mortality was for the proximal bile duct carcinoma 19%, for the middle bile duct carcinoma 11%, for distal bile duct carcinoma 0%, for the gallbladder carcinoma 10% and for the carcinoma of the papilla of Vater 4%.
info:eu-repo/classification/ddc/610, Medizin, Gallenblasenkarzinom, Gallenwegskarzinom
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