Multizentrische Studie zur Antibiotika-Resistenz von Streptococcus pneumoniae bei nicht-hospitalisierten Patienten mit Infektionen des Respirationstrakts in Deutschland, 1998-1999
In the last few years there was a worldwide observation of the growing resistance of pneumococcal to antibiotics. In Germany indeed there were only studies about invasive diseases caused by pneumococcals so far. The present study closes down this Vacancy of respiratory tract infections caused by pneumococcals. A total of 961 isolates of Streptococcus pneumoniae were examined from 19 different medical microbiology laboratories. During the sensivity testing the following resistance rates were shown: penicillin G 6.6%; clarithromycin 10.6%; tetracycline 13.9%; and levofloxacin 0.1%. Only 2 of 126 tetracycline-resistant pneumococcal yielded the existence of a tetO resistance genotype, the rest belonged to the tetM genotype. During the characterization of the makrolid-resistant pneumococcal there were 74% of the genera recognized as ermB-resistance genotype positive. 20.5% belonged to the mefE types of resistance, respectively. Four strains showed no PCR product in repeated assays. A total of 415 strains were serotyped. In order of decreasing frequency, 19F, 23F, 6B and 6A were the predominant types.
info:eu-repo/classification/ddc/610, Medizin, Streptococcus pneumoniae, Respirationstrakt, Resistenzraten, ermB, mefE, tetO, tetM, Serotyp
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