{"id":{"repo_id":"aachen","oai_identifier":"oai:publications.rwth-aachen.de:58840"},"canonical_url":"https://search.dev.ndltd.org/etd/aachen/oai:publications.rwth-aachen.de:58840","repository":{"repo_id":"aachen","name":"RWTH Aachen University","base_url":"https://publications.rwth-aachen.de/oai2d"},"display":{"title":"Numerische Simulation der Strömung in Miniaturkreiselpumpen zur Blutförderung","abstract":"New operation techniques on patients undergoing cardiovascular surgery or short-term ventricular assistance have lead to the development of a new generation of blood pumps with minimal size. This development is mainly focussed on hydraulic performance and biocompatibility. This thesis covers the assessment of computational fluid dynamics as a tool to investigate fluid dynamics and blood damaging effects within three intravascular micro blood pumps. In the beginning an introduction into computational fluid dynamics is given and the main assumptions with respect to the pump flow are presented. A computational model basing on these assumptions is introduced and requirements regarding grid generation, boundary conditions and further model parameters are discussed. Numerical calculations on this model are performed and analyzed. The results are compared with according experimental data from hydraulic tests and flow visualizations performed on physical blood pump models. Furthermore, the computational model is used to assess potential blood damage induced by the fluid dynamics within the pump. The physiological background of flow induced blood damage is discussed and different methods of damage assessment are presented. The most suitable computational approaches are implemented into the model, evaluated and validated against experimental data. Finally, the main results are summarized and discussed in context.","abstract_html":"New operation techniques on patients undergoing cardiovascular surgery or short-term ventricular assistance have lead to the development of a new generation of blood pumps with minimal size. This development is mainly focussed on hydraulic performance and biocompatibility. This thesis covers the assessment of computational fluid dynamics as a tool to investigate fluid dynamics and blood damaging effects within three intravascular micro blood pumps. In the beginning an introduction into computational fluid dynamics is given and the main assumptions with respect to the pump flow are presented. A computational model basing on these assumptions is introduced and requirements regarding grid generation, boundary conditions and further model parameters are discussed. Numerical calculations on this model are performed and analyzed. The results are compared with according experimental data from hydraulic tests and flow visualizations performed on physical blood pump models. Furthermore, the computational model is used to assess potential blood damage induced by the fluid dynamics within the pump. The physiological background of flow induced blood damage is discussed and different methods of damage assessment are presented. The most suitable computational approaches are implemented into the model, evaluated and validated against experimental data. 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This development is mainly focussed on hydraulic performance and biocompatibility. This thesis covers the assessment of computational fluid dynamics as a tool to investigate fluid dynamics and blood damaging effects within three intravascular micro blood pumps. In the beginning an introduction into computational fluid dynamics is given and the main assumptions with respect to the pump flow are presented. A computational model basing on these assumptions is introduced and requirements regarding grid generation, boundary conditions and further model parameters are discussed. Numerical calculations on this model are performed and analyzed. The results are compared with according experimental data from hydraulic tests and flow visualizations performed on physical blood pump models. Furthermore, the computational model is used to assess potential blood damage induced by the fluid dynamics within the pump. The physiological background of flow induced blood damage is discussed and different methods of damage assessment are presented. The most suitable computational approaches are implemented into the model, evaluated and validated against experimental data. Finally, the main results are summarized and discussed in context."]},{"key":"dc:source","label":"Dc Source","values":["Aachen : Publikationsserver der RWTH Aachen University VIII, 186 S. : Ill., graph. Darst. (2002). doi:10.18154/RWTH-CONV-120671 = Aachen, Techn. Hochsch., Diss., 2002"]},{"key":"dc:title","label":"Title","values":["Numerische Simulation der Strömung in Miniaturkreiselpumpen zur Blutförderung"]}]}],"canonical_facts":{"dc:contributor":["Rau, Günter"],"dc:coverage":["DE"],"dc:creator":["Apel, Jörn"],"dc:date":["2002"],"dc:description":["New operation techniques on patients undergoing cardiovascular surgery or short-term ventricular assistance have lead to the development of a new generation of blood pumps with minimal size. This development is mainly focussed on hydraulic performance and biocompatibility. This thesis covers the assessment of computational fluid dynamics as a tool to investigate fluid dynamics and blood damaging effects within three intravascular micro blood pumps. In the beginning an introduction into computational fluid dynamics is given and the main assumptions with respect to the pump flow are presented. A computational model basing on these assumptions is introduced and requirements regarding grid generation, boundary conditions and further model parameters are discussed. Numerical calculations on this model are performed and analyzed. The results are compared with according experimental data from hydraulic tests and flow visualizations performed on physical blood pump models. Furthermore, the computational model is used to assess potential blood damage induced by the fluid dynamics within the pump. The physiological background of flow induced blood damage is discussed and different methods of damage assessment are presented. The most suitable computational approaches are implemented into the model, evaluated and validated against experimental data. 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