Einfluss frühembryonaler Manipulation der Augenanlage auf das Verhalten und auf Positionsmarker im optischen Tektum des Haushuhns

To obtain a model for potential plasticity in the visual system of the chick we rotated one optic vesicle in embryos. The functionality of axonal connections was tested after hatching by examination of pecking behaviour, reflexes and the optokinetic nystagmus (OKN). The animal exhibited normal reflexes with both eyes, showing the functionality of the manipulated eye. The animal showed to a monocular optokinetic stimulus – a normal OKN – a direction asymmetry in response to different stimulus velocities – a dependence in response to stimulus velocity – an increase in gain with decreasing stimulation velocity. In pecking behaviour the animal optimised the pecking precision in the first 5 days by maturation of the target mechanism and by learning. Plasticity on molecular level was examined by showing the expression pattern of positional marker in the tectum opticum (TO) by complementary connecting proteins. The expression of ephrin A2/A5 was quantified in normal animals an those with one or two excised eye vesicles. Molecules were expressed in a gradient in a time frame between E9 and E15 in the TO. Thou enucleation of the eye anlage there was graded expression of ephrins between E11 and E15. The intensity of expression was influenced by the manipulation of the eye anlage. The results let us to the conclusion that on the molecular level the distribution patterns are mainly determined genetically and there just is a little influence by manipulation. On the behavioural level a higher amount of plasticity was shown.

Grantor dc:publisher

Publikationsserver der RWTH Aachen University

Year dc:date

2000

Author dc:creator

• Paryjas, Sandra

Contributors dc:contributor

• Wagner, Hermann

• info:eu-repo/classification/ddc/570
• Biowissenschaften, Biologie
• Huhn
• Tectum opticum
• Plastizität

Statement dc:rights

• info:eu-repo/semantics/openAccess

Language dc:language

ger

Identifier

https://publications.rwth-aachen.de/search?p=id:%22RWTH-CONV-118410%22

OAI record oai:identifier

https://publications.rwth-aachen.de/oai2d?verb=GetRecord&metadataPrefix=oai_dc&identifier=oai%3Apublications.rwth-aachen.de%3A56293