{"id":{"repo_id":"aachen","oai_identifier":"oai:publications.rwth-aachen.de:50123"},"canonical_url":"https://search.dev.ndltd.org/etd/aachen/oai:publications.rwth-aachen.de:50123","repository":{"repo_id":"aachen","name":"RWTH Aachen University","base_url":"https://publications.rwth-aachen.de/oai2d"},"display":{"title":"Zweidimensionale Strain-Echokardiographie zur Analyse der regionalen linksventrikulären Funktion bei Aortenklappenvitien vor und nach operativem Aortenklappenersatz","abstract":"In 53 patients scheduled for aortic valve replacement (22 with aortic stenosis (AS), 18 with aortic insufficiency (AI), 13 with aortic stenosis and insufficiency serial echocardiographic studies were performed pre- and postoperatively (within 7 days and at 6 months). Basal, mid and apical parasternal short-axis views were acquired (GE Vivid 7, Horton, Norway). Using a novel computer software (GE Ultrasound, Horton, Norway) which allows automatic frame-by-frame tracking of accoustic markers during the heart cycle radial and circumferential strain and strain rate were defined as parameters of myocardial deformation for each segment in a 16 segment model of the left ventricle.Results: Preoperatively segmental strain and strain rate data were not significantly different between the three aortic pathologies. Immediately postoperatively radial strain increased in the AS group (P<0.001), dropped in the AI group (P<0.001) and remained unchanged in the aortic stenosis and insufficiency group. During the subsequent 6 months follow-up radial strain increased significantly in all three groups. Similar changes were observed for the other strain and strain rate parameters. There was a significant correlation between the reduction in meridonial wall stress after aortic valve replacement for AS and increase in radial strain. Conclusions: Myocardial deformation parameters change significantly soon after aortic valve replacement for aortic stenosis or aortic insufficiency indicating a significant dependency of determined myocardial deformation parameters on left ventricular preload and afterload. During the subsequent 6 months follow-up myocardial deformation increases indicating improvement in myocardial contractility.","abstract_html":"In 53 patients scheduled for aortic valve replacement (22 with aortic stenosis (AS), 18 with aortic insufficiency (AI), 13 with aortic stenosis and insufficiency serial echocardiographic studies were performed pre- and postoperatively (within 7 days and at 6 months). Basal, mid and apical parasternal short-axis views were acquired (GE Vivid 7, Horton, Norway). Using a novel computer software (GE Ultrasound, Horton, Norway) which allows automatic frame-by-frame tracking of accoustic markers during the heart cycle radial and circumferential strain and strain rate were defined as parameters of myocardial deformation for each segment in a 16 segment model of the left ventricle.Results: Preoperatively segmental strain and strain rate data were not significantly different between the three aortic pathologies. Immediately postoperatively radial strain increased in the AS group (P&lt;0.001), dropped in the AI group (P&lt;0.001) and remained unchanged in the aortic stenosis and insufficiency group. During the subsequent 6 months follow-up radial strain increased significantly in all three groups. Similar changes were observed for the other strain and strain rate parameters. There was a significant correlation between the reduction in meridonial wall stress after aortic valve replacement for AS and increase in radial strain. Conclusions: Myocardial deformation parameters change significantly soon after aortic valve replacement for aortic stenosis or aortic insufficiency indicating a significant dependency of determined myocardial deformation parameters on left ventricular preload and afterload. During the subsequent 6 months follow-up myocardial deformation increases indicating improvement in myocardial contractility.","abstract_has_math":false,"creators":["Kramann, Rafael"],"institution":"Publikationsserver der RWTH Aachen University","degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":null,"school":null,"contributors":["Hoffmann, Rainer"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2008,"date_issued":"2008","date_published":"2008","updated_at":"2026-07-30T19:40:16Z","subjects":["info:eu-repo/classification/ddc/610","Ultraschallkardiographie","B-scan-Ultraschallkardiographie","Aortenklappenersatz","Aortenstenose","Aorteninsuffizienz","Aortenklappenfehler","Medizin","strain","vorlast","nachlast","hämodynamik","echokardiography","two-dimensional","preload","afterload"],"languages":["ger"],"rights":["info:eu-repo/semantics/openAccess"],"rights_urls":[],"identifier_entries":[{"key":"dc:identifier","label":"Identifier","values":["https://publications.rwth-aachen.de/search?p=id:%22RWTH-CONV-112680%22"],"render_values":[{"text":"https://publications.rwth-aachen.de/search?p=id:%22RWTH-CONV-112680%22","href":"https://publications.rwth-aachen.de/search?p=id:%22RWTH-CONV-112680%22","code":true}]}]},"links":{"outbound_url":"https://publications.rwth-aachen.de/record/50123","outbound_label":"Repository record","outbound_source":"dc:identifier"},"source_record":{"url":"https://publications.rwth-aachen.de/oai2d?verb=GetRecord&metadataPrefix=oai_dc&identifier=oai%3Apublications.rwth-aachen.de%3A50123","prefix":"oai_dc"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Hoffmann, Rainer"]},{"key":"dc:creator","label":"Author","values":["Kramann, Rafael"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:coverage","label":"Dc Coverage","values":["DE"]},{"key":"dc:date","label":"Dc Date","values":["2008"]},{"key":"dc:publisher","label":"Institution","values":["Publikationsserver der RWTH Aachen University"]},{"key":"dc:relation","label":"Dc Relation","values":["info:eu-repo/semantics/altIdentifier/urn/urn:nbn:de:hbz:82-opus-23951"]},{"key":"dc:type","label":"Dc Type","values":["info:eu-repo/semantics/doctoralThesis","info:eu-repo/semantics/publishedVersion"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["info:eu-repo/classification/ddc/610","Ultraschallkardiographie","B-scan-Ultraschallkardiographie","Aortenklappenersatz","Aortenstenose","Aorteninsuffizienz","Aortenklappenfehler","Medizin","strain","vorlast","nachlast","hämodynamik","echokardiography","two-dimensional","preload","afterload"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language","label":"Dc Language","values":["ger"]},{"key":"dc:rights","label":"Dc Rights","values":["info:eu-repo/semantics/openAccess"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["https://publications.rwth-aachen.de/record/50123","https://publications.rwth-aachen.de/search?p=id:%22RWTH-CONV-112680%22"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["In 53 patients scheduled for aortic valve replacement (22 with aortic stenosis (AS), 18 with aortic insufficiency (AI), 13 with aortic stenosis and insufficiency serial echocardiographic studies were performed pre- and postoperatively (within 7 days and at 6 months). Basal, mid and apical parasternal short-axis views were acquired (GE Vivid 7, Horton, Norway). Using a novel computer software (GE Ultrasound, Horton, Norway) which allows automatic frame-by-frame tracking of accoustic markers during the heart cycle radial and circumferential strain and strain rate were defined as parameters of myocardial deformation for each segment in a 16 segment model of the left ventricle.Results: Preoperatively segmental strain and strain rate data were not significantly different between the three aortic pathologies. Immediately postoperatively radial strain increased in the AS group (P<0.001), dropped in the AI group (P<0.001) and remained unchanged in the aortic stenosis and insufficiency group. During the subsequent 6 months follow-up radial strain increased significantly in all three groups. Similar changes were observed for the other strain and strain rate parameters. There was a significant correlation between the reduction in meridonial wall stress after aortic valve replacement for AS and increase in radial strain. Conclusions: Myocardial deformation parameters change significantly soon after aortic valve replacement for aortic stenosis or aortic insufficiency indicating a significant dependency of determined myocardial deformation parameters on left ventricular preload and afterload. During the subsequent 6 months follow-up myocardial deformation increases indicating improvement in myocardial contractility."]},{"key":"dc:source","label":"Dc Source","values":["Aachen : Publikationsserver der RWTH Aachen University VI, 91 S. : Ill., graph. Darst. (2008). = Aachen, Techn. Hochsch., Diss., 2008"]},{"key":"dc:title","label":"Title","values":["Zweidimensionale Strain-Echokardiographie zur Analyse der regionalen linksventrikulären Funktion bei Aortenklappenvitien vor und nach operativem Aortenklappenersatz"]}]}],"canonical_facts":{"dc:contributor":["Hoffmann, Rainer"],"dc:coverage":["DE"],"dc:creator":["Kramann, Rafael"],"dc:date":["2008"],"dc:description":["In 53 patients scheduled for aortic valve replacement (22 with aortic stenosis (AS), 18 with aortic insufficiency (AI), 13 with aortic stenosis and insufficiency serial echocardiographic studies were performed pre- and postoperatively (within 7 days and at 6 months). Basal, mid and apical parasternal short-axis views were acquired (GE Vivid 7, Horton, Norway). Using a novel computer software (GE Ultrasound, Horton, Norway) which allows automatic frame-by-frame tracking of accoustic markers during the heart cycle radial and circumferential strain and strain rate were defined as parameters of myocardial deformation for each segment in a 16 segment model of the left ventricle.Results: Preoperatively segmental strain and strain rate data were not significantly different between the three aortic pathologies. Immediately postoperatively radial strain increased in the AS group (P<0.001), dropped in the AI group (P<0.001) and remained unchanged in the aortic stenosis and insufficiency group. During the subsequent 6 months follow-up radial strain increased significantly in all three groups. Similar changes were observed for the other strain and strain rate parameters. There was a significant correlation between the reduction in meridonial wall stress after aortic valve replacement for AS and increase in radial strain. Conclusions: Myocardial deformation parameters change significantly soon after aortic valve replacement for aortic stenosis or aortic insufficiency indicating a significant dependency of determined myocardial deformation parameters on left ventricular preload and afterload. During the subsequent 6 months follow-up myocardial deformation increases indicating improvement in myocardial contractility."],"dc:identifier":["https://publications.rwth-aachen.de/record/50123","https://publications.rwth-aachen.de/search?p=id:%22RWTH-CONV-112680%22"],"dc:language":["ger"],"dc:publisher":["Publikationsserver der RWTH Aachen University"],"dc:relation":["info:eu-repo/semantics/altIdentifier/urn/urn:nbn:de:hbz:82-opus-23951"],"dc:rights":["info:eu-repo/semantics/openAccess"],"dc:source":["Aachen : Publikationsserver der RWTH Aachen University VI, 91 S. : Ill., graph. Darst. (2008). = Aachen, Techn. Hochsch., Diss., 2008"],"dc:subject":["info:eu-repo/classification/ddc/610","Ultraschallkardiographie","B-scan-Ultraschallkardiographie","Aortenklappenersatz","Aortenstenose","Aorteninsuffizienz","Aortenklappenfehler","Medizin","strain","vorlast","nachlast","hämodynamik","echokardiography","two-dimensional","preload","afterload"],"dc:title":["Zweidimensionale Strain-Echokardiographie zur Analyse der regionalen linksventrikulären Funktion bei Aortenklappenvitien vor und nach operativem Aortenklappenersatz"],"dc:type":["info:eu-repo/semantics/doctoralThesis","info:eu-repo/semantics/publishedVersion"]},"updated_at":"2026-07-30T19:40:16Z"}