Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"zyxin"”.
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Zyxin signaling: Protease-activated receptor-1 and Rho guanine nucleotide exchange factor p114.
Zyxin signaling: Protease-activated receptor-1 and Rho guanine nucleotide exchange factor p114.
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Molecular and Cellular Mechanisms of LIM Protein Mechanotransduction
… fibroblasts, I identified the zyxin, FHL, and paxillin families of tandem LIM domain proteins to be mechanoresponsive cytoskeletal proteins. A single conserved phenylalanine in each LIM domain was identified to be necessary for mechanosensitivity. Through development of an in …
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Understanding HNF-1β through Identification of Interacting Proteins and Target Genes in the Kidney
… binding partners of HNF-1Beta in the kidney. Zyxin and LPP were isolated as putative interacting proteins. The LIM-containing proteins, Zyxin and LPP, are focal adhesion proteins that shuttle between the cytoplasm and nucleus and play a role in the architectural organization of cells. Both …
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Diverse functions for intern associated proteins in Drosophila adult muscle
… the IAPs FAK, RSU1, tensin, vinculin and zyxin are not required for viability or embryonic muscle attachment. Furthermore, FAK, RSU1, tensin and vinculin have been observed to localise to muscle attachment sites in Drosophila, indicating that they have some function in muscle attachment. …
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NMR AS A TOOL TO QUANTITATIVELY CHARACTERIZE MOLECULAR MECHANISMS GOVERNING ACTIN DYNAMICS AND RICE LATERAL ROOT DEVELOPMENT
… (VASP) and the cytoskeleton protein Zyxin was determined. This interaction is important for cellular shape, cell motility and stress fiber repair. This study presented a model for a mechanism of action where phosphorylation can act as a stoichiometric switch and can explain the …
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STEP-enabled Force Measurement Platform of Single Migratory Cells
… and temporal organization of focal adhesion zyxin in response to single cell migration on these networks.
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Smooth Muscle Hyperplasia Due to Acta2/Myh11 Mutations: Identification of Novel Pathology and Pathways Leading to Aneurysms and Diverse Vascular Occlusive Diseases
… SMCs showed altered localization of vinculin and zyxin and increased phosphorylated focal adhesion kinase (FAK) in focal adhesions. A specific FAK inhibitor decreased Acta2-/- SMC proliferation to levels equal to wildtype SMCs (p<0.05), suggesting that FAK activation leads to the increased …
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Integrin-vermittelte Invasion von Staphylococcus aureus in Säugerzellen
… Talin, Vinculin, Paxillin, Tensin, -Actinin oder Zyxin sowie Signalenzymen wie der Fokalen Adhäsions Kinase (FAK) oder Kinasen der Src Familie. Die Protein Tyrosin Kinase (PTK) FAK ist nach Integrinstimulierung eines der Schlüsselenzyme in FK. Dies war der Anlass nach der Bedeutung von FAK für die …