Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"zymogen granules"”.
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Altered Morphology And Composition Of Zymogen Granules In Acute Pancreatitis
… secreted following a meal are stored as inactive zymogens within membrane bound secretory vesicles called Zymogen Granules (ZG), and activated extracellularly. In acute pancreatitis however, the digestive enzymes are prematurely activated within the cell, resulting in autodigestion of the tissue. …
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Comparison of the Protein Contents of Bovine Zymogen Granules and of Pancreatic Juice
<p>A zymogen granule fraction has been isolated from bovine pancreas by differential centrifugation under conditions designed to favor homogeneity at the expense of yield. The fraction has been examined in the electron microscope and found to contain a limited amount of contamination represented by …
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The Role of Microtubules in Secretion
… been implicated in the movement of secretory granules to the cell membrane in a variety of both exocrine and endocrine cells. A range of roles, from provision of the motive force to preventing presecretory movement, have been attributed to these organelles. An in vitro model system to …
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The Role of Munc18 Proteins in Physiologic and Pathologic Exocytoses in the Pancreatic Acinar Cell
… is mis-targeting and deregulated fusion of zymogen granules with lysosomal bodies in the acinar cells. This derangement results in premature activation of proteolytic zymogens and autophagic digestion of cellular contents. I have hypothesized an alternate mechanism, which is pathologic …
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The daily rhythm of Paneth cells in <i>Mus musculus </i>
… contain large (1-3 u) spherical, acidophilic granules. As seen with the light microscope (LM), Paneth cells have basal basophilia (an indication of ribosomes), a basally located, often deeply indented nucleus, a supranuclear Golgi apparatus, and secretory granules in the supranuclear region …