Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"zinc transporter"”.
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Die Bedeutung von Zinkionen für mononucleäre Leukocyten
Zinc is an essential trace element for the immune system. In this work, important influences of zinc on mononuclear cells were examined.For the first time, a direct stimulation of cells by zinc could be shown, which was dependent on zinc concentration and could not be induced by other cations. Even …
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Anatomy and Function of Synaptic Zinc in the Striatum
Synaptic zinc is located in many regions of the brain. One area that contains a high amount is the input center of the basal ganglia: the striatum. Environmental enrichment was used to examine potential changes in morphology of striatal cells of mice with (ZnT3 wildtype) and without (ZnT3 knockout) …
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Temporal and Tissue Specific Changes in Expression of Nutrient Transporters and Host Defense Peptides in Young Broilers during Salmonella and Campylobacter infections
… the influence on mRNA abundance of nutrient transporters and host defense peptides (HDPs) during a Salmonella or a Campylobacter challenge in young commercial broilers. Comparisons were made between non-challenged and challenged (106, 107, or 108 colony forming units of Salmonella or …
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Next-Generation version of pseudomonas exotoxin a based immunotoxins with reduced immunogenicity for triple negative breast cancer (TNBC) treatment
… failed such as chemotherapy. Overexpression of zinc transporter (LIV-1) and trophoblast cell surface antigen-2 (trop2) has been implicated in the oncogenesis of TNBC and associated with an unfavorable prognosis. Consequently, the LIV-1 and TROP-2 biomarkers represent a specific target antigen …
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Maf and Mitf transcription factors regulate pancreatic endocrine cell differentiation and function
… show that Neuronatin (Nnat), islet-specific zinc transporter (Slc30a8), islet-specific glucose-6-phosphatase catalytic subunit-2 protein (G6pc2) and Microphthalmia associated transcription factor (Mitf) are downregulated in embryonic and adult mutant pancreata. In contrast, the mRNA level of …
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Die Regulation der Zinktransporter und ihr Einfluss auf die intrazelluläre Zinkhomöostase in Leukocyten
Zinc is an essential trace element for the immune system. During this work, important mechanisms regarding the intracellular zinc homeostasis and its influence on intracellular signal transduction in mononuclear cells could be elucidated. The analysis of the expression of zinc exporters, together …