Global ETD Search
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Showing 1 to 2 of 2 for “"zinc diethyldithiocarbamate"”.
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Investigation of the anticancer activity and mechanisms of zinc diethyldithiocarbamate in multiple myeloma
… with transition metals such as copper and zinc to form metal-metabolite complexes (zinc/copper diethyldithiocarbamate), which are the active anticancer compounds. Diethyldithiocarbamate (DDC), a metabolite of DS, has previously been trialled in clinics to treat HIV patients due to its …
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In vitro investigation of the anticancer activity and molecular mechanisms of action of albumin nano-encapsulated copper/zinc diethyldithiocarbamate in human pancreatic cancer cells
… chelated with Cu²⁺ or Zn²⁺ ions to form copper diethyldithiocarbamate (Cu(DDC)₂) or zinc diethyldithiocarbamate (Zn(DDC)₂). However, the clinical anticancer application of DSF is hindered by a short plasma half-life (<4 minutes) and bioavailability challenges from separate Cu/Zn supplementation. …