Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"yeast mating"”.
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Mechanisms of Gradient Tracking During Yeast Mating
… of temporal integration is unknown. We used the mating response of the budding yeast, <italic>Saccharomyces cerevisiae</italic>, as a model to study eukaryotic gradient tracking. </p><p>During mating, yeast cells polarize and grow up a gradient of pheromone to find and fuse with opposite-sex …
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Models and analysis of yeast mating response : tools for model building, from documentation to time-dependent stimulation
… signaling systems. In particular, studies of the mating pheromone response system in yeast (Saccharomyces cerevisiae) have revealed many protein families and regulatory motifs also found in higher eukaryotes. This thesis develops several computational and experimental approaches that facilitate …
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Synthetic sensing systems in Saccharomyces cerevisiae
The yeast Saccharomyces cerevisiae is a major chemical production platform in the biotechnological industry. It is also increasingly being used as a whole cell biosensor. One method of developing such whole cell biosensors in yeast is by exploiting its mating pathway, which is normally induced by …
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Alternative rownstream roles for Ste2p and an α-arrestin in sacccharomyces cerevisiae mating
Ste2p and Ste3p are well-characterized yeast pheromone G-protein Coupled Receptors (GPCR) those are involved in the signaling of mating responses that lead to cell fusion. Their signaling–associated interactions with G-protein/MAPK signal transduction machinery are well established, homologous to …
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Lipid rafts in protein sorting and yeast cell polarity
… exploitation for cell surface polarity in the yeast Saccharomyces cerevisiae. To this end, we conducted a genome wide screen that identified yeast mutants defective in cell surface delivery of the model cargo protein FusMid-GFP. The most striking result of this screen was that mutant strains …
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Systematic and combinatorial approaches for metabolic engineering of optimal yeast strains to produce fuels and chemicals
… engineering approach for developing optimal yeast cell factories capable of efficiently fermenting various sugars abundant in renewable biomass. The research has broad applications for sustainable biological production of value-added fuels and chemicals. Initially, a systematic approach based …
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Inferring Transcriptional and Post-Transcriptional Network Structure by Exploiting Natural Sequence Variation
… populations of Saccharomyces cerevisiae (baker’s yeast) as well as Caenorhabditis elegans (roundworm). The first study focused on inferring the in vitro binding specificity of RNA-binding proteins (RBPs). We first analyzed a recent compendium of in vivo mRNA binding data to model the sequence …
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Fast Sweeping Methods for Steady State Hyperbolic Conservation Problems and Numerical Applications for Shape Optimization and Computational Cell Biology
… biological process called cell polarization. Yeast cell mating is a well-studied biological system which involves external chemical stimuli, reactions and surface diffusion of multiple proteins on the cell membrane. In this part, we use the level set method to do the simulation and couple it …