Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 30 for “"xerostomia"”.
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A comparison of two saliva substitutes in the management of xerostomia during radiotherapy for cancer of the head and neck
… saliva substitutes to ameliorate the effects of xerostomia is well established and proper advice and access to relevant preparations is essential.
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Η σιελομετρία και ανίχνευση αντισωμάτων στο σίελο, ως διαγνωστικές παράμετροι στο σύνδρομο Sjogren
… including the salivary glands resulting in xerostomia. The hyperreactivity of the immune system is an integral component of primary Ss (1oSs), as exemplified by various serum autoantibodies [including antibodies to Ro(SSA) and La(SSB) cellular antigens] and the infiltration of the exocrine …
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Salivary analysis in dogs undergoing definitive radiation therapy for head and neck cancer
Xerostomia ("dry mouth") is one of the most common side effects of radiotherapy of head and neck tumors (HNT) in people and can significantly impact a patient's quality of life post-treatment. Aside from causing dry mouth, this condition may affect chewing, swallowing, and oral health. There are …
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Investigating the role of macrophage-epithelial cell interaction in salivary gland regeneration
… suffer from a devastating side effect known as xerostomia (chronic dry-mouth), which results from irreversible salivary gland hypofunction. Although xerostomia has a detrimental impact on patient quality of life, there are currently no long-term solutions to restore salivary gland function, and …
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Diabetes mellitus and oral health: a comparison between diabetic and non-diabetic subjects
… among others, gingivitis, periodontal disease, xerostomia, oral candidiasis, dental caries, periapical abscesses, lichen planus,burning mouth syndrome and an altered taste sensation (Lamster et al. 2008; Skamagas et al. 2008; Vernillo, 2003). The aim of the present study was to compare the oral …
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Estudo clínico de fase II e farmacocinético para o uso de talidomida em pacientes com câncer colorretal metastático
… efeitos colaterais a sonolência, a tontura, a xerostomia e a constipação. Não houve nenhuma resposta objetiva ou doença estável após oito semanas de tratamento. A sobrevida global mediana foi de 3,6 meses. A talidomida é bem tolerada como agente único de tratamento, mas não demonstrou nenhuma …
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Dental Utilization for Medicaid-‐Enrolled Children with Cystic Fibrosis
… cariogenic diet and frequent use of inhaled xerostomia-inducing medications, children with CF are believed to be at a lower risk for dental caries (tooth decay) compared to other children. A potential protective factor is increased use of preventive dental care, but not studies to date have …
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Estudo da farmacocinética da talidomida em pacientes com tumores sólidos refratários
… efeitos colaterais a sonolência, a tontura, a xerostomia e a constipação. Não foram observadas respostas tumorais objetivas. Para avaliar os parâmetros farmacocinéticos da talidomida foram coletadas amostras de sangue imediatamente antes da administração da droga, 1h, 2h, 2,5h, 3h, 3,5h, 4h, …
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Burning Mouth Syndrome: a demographic and comorbid condition case series
… and stress reduction. Comorbid Conditions: Xerostomia 35.8%, Candida 21.1%, Bad Taste 29.5%, Post-menopausal 72.6%, Vaginal Dryness 20%, Sleep Disturbance 45%, Anxiety 36.8%, Depression 29.5%, Depression & Anxiety 20%, Hypothyroidism 20%. Conclusions: Because of prevalence it seems …
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Tissue-Specific Matrix Control of Cell Cohesion and Migration Signaling Complexes
… those patients with damaged glands experiencing xerostomia/dry mouth and in need of salivary gland restoration or patients with PCa metastases. </p>
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Can Intensity-Modulated Radiotherapy (IMRT) Be Used To Reduce Toxicity And Improve Tumour Control In Patients With Head And Neck Cancer?
… that IMRT significantly reduced patient-reported xerostomia, allowed recovery of saliva production and improved quality of life. The second part of the thesis describes pre-clinical evaluation of techniques to escalate radiation dose in patients with larynx and hypopharynx tumours. A phase I/II …
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A mathematical study of the role of calcium in the regulation of saliva secretion
Xerostomia is estimated to affect 30% of adults over the age of 65. The condition is characterised by a lack of saliva secretion, resulting in a range of health problems. A rise in the concentration of free cytosolic calcium (Ca²⁺) is essential to initiate saliva secretion. We construct …
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Análise da efetividade do tratamento medicamentoso em crianças e adolescentes obesos
… as seguintes reações adversas: cefaléia, xerostomia, obstipação, equimoses. Discussão: na maioria dos estudos registra-se maior redução do IMC no grupo experimental como principal desfecho observado. Em relação ao aumento da sensibilidade e redução da resistência à insulina, houve …
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Late-Effect Symptoms, Tobacco and Alcohol Use, and Demoralization in Head and Neck Cancer Survivors
… physical symptoms such as but not limited to xerostomia, mucositis, dysphagia, pain and fatigue, tobacco and alcohol use, and demoralization among head and neck cancer survivors. Descriptive statistics were reported for the occurrence and intensity of late-effect physical and life interference …
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A Systems Approach to Modelling Tumour and Tissue Response in Radiotherapy for Head-and-Neck Cancer
… Common genetic variants associated with acute xerostomia and late dysphagia were identified, providing insights into the genetic basis of treatment response; however, larger national and international cohorts are needed to validate these findings. At the treatment level, a novel spatial mapping …
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The Role of Circadian Clock in the Embryonic and Post-Natal Development and Pathophysiology of Oral Tissues and Implications of Natural Treatments in Dental Caries Progression
… resulting in symptoms such as dry mouth (xerostomia). The SG dysfunction not only affects oral health, leading to an increased susceptibility to dental caries, but also has potential systemic implications. The circadian clock, an endogenous intracellular mechanism, assumes a pivotal role …
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The Modulation Of Mucosal Immune Markers, Urs, And Psychological Parameters Following Acute And Chronic Exercise
… may be a benefit for people suffering from xerostomia. Additionally, participation in an acute exercise session of aerobic or yoga exercise may elevate SIgA concentration immediately following exercise indicating strengthened mucosal immunity. </p> <p>Since SAA is a relatively new …
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Functional Restoration of Irradiated Salivary Glands Through Modulation of aPKCζ and Nuclear Yap in Salivary Progenitors
… radiation therapy, and salivary hypofunction and xerostomia occur in 60-85% of these patients due to irreversible damage to the salivary glands. Current preventative and palliative care fail to improve quality of life, accentuating the need for regenerative therapies. Stem/progenitor-cell based …
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A study of a multi-systemic immune-mediated disease in the English Cocker Spaniel
… proteinuria, anal gland disease, suspected xerostomia, atopy and other immune-mediated diseases. A strong association between CP and ECS presenting blue roan coat colour was seen, suggesting a link between coat colour and immune-mediated conditions in this breed. Moreover, the development of …
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Diabetes-related ultrastructural and immunohistochemical changes in human salivary gland parenchyma and a study on a native scaffold obtained from salivary gland stroma
… give rise to salivary gland degeneration and xerostomia, but the therapies commonly used are not satisfactory so far. An emerging alternative approach to ameliorate the life quality of xerostomic patients is the regeneration of salivary parenchyma. A “Native Human Submandibular Gland Scaffold” …
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