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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 315 for “"xenopus"”.
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Endodermal Patterning in Xenopus laevis
… expressed endodermal genes in $\textit{Xenopus laevis}$, a classic embryological model organism. Here, I report the identification and characterisation of a dozen novel regionally expressed endoderm genes. At tailbud stages their expression patterns fall into three re-occurring domains, …
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Cellular principles of Xenopus appendage regeneration
… principles driving this ability, I investigated Xenopus laevis tadpoles. Tadpoles can regrow their lost tails and limbs only at specific developmental stages, allowing comparative studies to determine principles of regeneration. I first compared tail amputation responses of regeneration-competent …
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The chromatic function in Xenopus Laevis
In few Amphibia is the extent of visible pigmentary effector activity as striking as in the case of the South African clawed toad. Nevertheless, there is no account on record of the phenomena of colour response in this species.
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Role of Xenopus Pitx3 during early development.
… focus of this study was to elucidate the role of Xenopus Pitx3 during eye development. As a side project, we also studied the role of this gene in the left-right patterning and axis formation in Xenopus. Here, we report the cloning of a Xenopus homolog which encodes a conceptual protein of 292 …
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Transcriptional Regulation of the Xenopus MyoD Gene
… of the MyoD gene itself has not studied in Xenopus. In this thesis, I have analyzed the transcriptional regulatory mechanism of the MyoD gene in Xenopus by different approaches, which include transgenic reporter analysis of its cis-regulatory elements of MyoD transcription and …
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FGF signaling in Xenopus laevis lens regeneration
The larvae of the frog Xenopus laevis is capable of regenerating lenses. In this re- generative process, the corneal tissue is capable of forming a lens after removal of the original lens, but the molecular mechanisms for this process is unknown. This dissertation examines the relationship between …
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Příprava transgenní kultury testikulárních kmenových buněk Xenopus tropicalis.
… kmenových buněk je vhodným modelovým organismem Xenopus tropicalis. Tento obojživelník se vyznačuje vnějším oplozením a embryonálním vývojem značného množství zárodků v rámci jedné snůšky. Oocyty a embrya jsou dostatečně velká (kolem 1 mm) a tím i vhodná pro mikromanipulační zásahy. Laboratoř …
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Molecular Control of Lens Development in Xenopus Laevis
… during embryonic lens formation. In the anuran, Xenopus laevis, there is an alternative lens-forming process termed cornea-lens transdifferentiation. Considering that both lens-forming processes result in the same ultimate outcome, it begs the question: How related are the molecular events …
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Paxillin is a Novel Regulator of Xenopus Oocyte Maturation
… recognized essential regulator of meiosis in Xenopus leavis oocytes. Reduction of Paxillin expression using RNA interference and antisense oligonucleotides completely abrogates steroid-triggered meiotic resumption. Detailed signaling studies reveal that Paxillin is acting early in the kinase …
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Controlled ablation of rod photoreceptors in transgenic Xenopus laevis
Retinal degeneration is the progressive loss of neurons lining the posterior surface of the eye. Loss of a certain group of neurons called rod photoreceptors can occur as the result of genetic mutation. In humans, and in mammalian models of retinal degeneration, the death of these cells is …
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Die Regulation der Pankreasentwicklung von Xenopus laevis durch Transkriptionsfaktornetzwerke
… bestimmt. Es wurde bereits beschrieben, dass in Xenopus laevis der Retinsäure (RA)- signalweg für die Entwicklung der dorsalen Pankreasanlage als auch für die endokrine Zelldifferenzierung bereits während der Gastrulation notwendig ist. Es wurde ebenfalls gezeigt, dass eine gemeinsame Expression …
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Mechanisms and Regulation of Organelle Transport in Xenopus Melanophores
… issues by studying pigment granule motility in Xenopus melanophores. These dermal cells are able to cyclically transport pigment granules, termed melanosomes, either to aggregate to the cell center or disperse throughout the cell in response to hormonal stimulus to effect color changes in the …
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Estrogen Receptor Regulation of Xenopus Laevis Vitellogenin Gene Expression
The mechanism by which the Xenopus laevis estrogen receptor mediates the transcriptional response of the vitellogenin gene was investigated. The Xenopus estrogen receptor (XER) cDNA was cloned and sequenced. It could encode a protein of 66 Kd, which is approximately the same size as human and …
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Cellular and Developmental Functions of The Xenopus Arvcf-Catenin:Kazrin Complex
Xenopus ARVCF (xARVCF), a member of p120-catenin subfamily, binds cadherin cytoplasmic domains to enhance cadherin metabolic stability, or when dissociated, modulates Rho-family GTPases. We previously found that xARVCF binds directly to Xenopus KazrinA (xKazrinA), a widely expressed, conserved …
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De ontwikkeling van het ruggemerg van de klauwpad, Xenopus laevis
Contains fulltext : mmubn000001_02662110x.pdf (Publisher’s version ) (Open Access)
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Regulation der Neurogenese durch bHLH-O-Proteine in Xenopus laevis
… bHLH-O-Proteine besser zu verstehen, wurden in Xenopus neue Mitglieder der bHLH-O-Proteinfamilien in silico identifiziert und einige dieser Proteine näher charakterisiert.In dieser Arbeit konnte ein in Xenopus bisher noch nicht beschriebenes Hairy und E(spl) verwandtes Protein identifiziert …
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