Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 548 for “"x-ray crystallography"”.
-
Protein Mechanics Through X-Ray Crystallography
… show that cycles of mutagenesis coupled with X-ray crystallography can reveal an anisotropic, distributed pattern of physical interactions in a PDZ domain, PSD-95 PDZ3. This pattern is functionally important and deeply connected to the evolution of PDZ domains in general. Second, we present a …
-
X-ray Crystallography of Inositol Dehydrogenase Enzymes
… differences in stereoisomer selectivity by X- ray crystal structure analysis and comparison. High resolution apo, binary, and ternary crystal structures for iolG1 and iolG2 wild type enzymes were determined. For iolG1 the ternary structures were determined for myo-inositol and d-chiro-inositol …
-
Solid-State Chemistry of Benzophenone Anils (x-Ray, Crystallography)
… of some benzophenone anils were determined by X-ray diffraction. In five of the six structures the molecules adopted the trans configuration. The strong preference for this isomer in the solid state is in sharp contrast to the behavior in solution where previous workers found that both isomers …
-
X-ray crystallography for the study of nickel and iron salicylaldimines
<p>"X-ray diffraction of single crystals has developed dramatically over the last century by combining fundamental theories of light, diffraction, and statistics to generate the complete, geometric structure of molecules. The quality of the resulting X -ray structure data are reported in R₁ < 5%, …
-
SAXS and X-ray Crystallography Studies of the Cellulosome from Clostridium thermocellum
… heterodimeric complex. However, small angle X-ray scattering (SAXS) studies indicate that this dimerization does not occur in solution. The crystal structures and additional SAXS studies reveal flexibility in the CohI9—X linker that is surprisingly restricted to two dimensions. In addition, …
-
The structure and flexibility of myoglobin : molecular dynamics and x-ray crystallography
Thesis: Ph. D., Massachusetts Institute of Technology, Department of Chemistry, 1986
-
Structural Studies of DNA Replication Proteins by X-Ray Crystallography and Molecular Dynamics
… of the chromosomal replicase assembly through X-ray crystallography and molecular dynamics simulations. First, a crystal structure of the DNA polymerase from archaebacterium Desulfurococcus Tok (D. Tok Pol) was solved at 2.4 Å. The structure revealed its similarity to that of the DNA polymerase …
-
Global Optimization in Least Squares Problems in FTIR Spectroscopy and X -Ray Crystallography
… the thesis considers the ""phase problem"" in X-ray crystallography. In particular, we address the problem of estimating the three-dimensional atomic positions of crystal structures from diffraction measurements alone. Starting from the ""minimal principle"" model, we develop novel optimization …
-
Interaction of B-DNA and Monovalent Cations: Theory and Practice in X-Ray Crystallography
… nature of the solvent/counter-ion region of x-ray crystal structures are raised. The ambiguity in the identity and occupancy of the molecular and atomic species in this region is explored experimentally. Anomalous scattering is proposed as a possible method for resolving this ambiguity. To this …
-
Effects of a carcinogenic alkyl lesion on DNA: A structural study by x-ray crystallography
… the $\rm e\sp6G$ lesion has been determined by X-ray crystallography. The DNA dodecamer d(CGC ($\rm e\sp6G$) AATTCGCG) could be crystallized only when complexed to minor groove binding drugs like Hoechst 33258, Hoechst 33342, Netropsin, as well as SN6999. In addition, the native dodecamer …
-
Structural Determination of the novel Universal Stress Protein G4LZI3 from Shistosoma mansoni using X-ray Crystallography
… Protein G4LZI3 from Schistosoma mansoni using X-ray Crystallography Priscilla Masamba PhD (Biochemistry) thesis, Department of Biochemistry and Microbiology, Faculty of Science and Agriculture, University of Zululand Schistosoma mansoni is a parasitic multicellular helminth of the …
-
Structural characterization of the lysosomal 66.3 kDa protein and of the DNA repair enzyme Mth0212 by means of X-ray crystallography
Diese Doktorarbeit gliedert sich in zwei Abschnitte, welche beide die strukturelle Charakterisierung von Makromolekülen mittels Röntgenkristallographie beinhalten. Abschnitt I befasst sich mit dem lysosomalen 66.3 kDa - Protein aus Maus, dessen zelluläre Funktion bislang nicht bekannt ist. In …
-
Structural analysis via X-ray crystallography of an engineered carbon methyltransferase, a phytoxic phosphonate and its modifying enzyme, and a chimeric tyrosinase
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2027-05-01
-
Synthesis and X-ray Diffraction Structures of 2-(2-thienylidene)-4,5-bis-(diphenylphosphino)-4-cyclopenten-1,3-dione and fac-BrRe(CO)3[2-(2-thienylidene)-4,5-bis(diphenylphosphino)-4-cyclopenten-1,3-dione]
… structure of the ligand was determined using X-ray crystallography. When the ligand was treated with the solvent stabilized intermediate of ReBr(CO)5 with THF, a monomeric metal complex, fac-BrRe(CO)3[2-(2-thienylidene)-4,5-bis(diphenylphosphino)-4-cyclopenten-1,3-dione] was the result. The …
-
Azobenzene, Diphenylacetylene and Aromatic Nitrogen Heterocycles Coordinated to Early Transition Metal Metallocenes
… (IV) were determined using X-ray crystallography.
-
Molecular Magnetism: The Design, Synthesis, and Characterization of New Building Blocks for Molecule-based Magnetic Materials
… three ligands have been fully characterized by X-ray crystallography. [molecular structure diagram will not copy here, but is available in full pdf.] The coordination chemistry of these ligands with divalent first row transition metal ions was investigated. For ligand (H2L1), the molecular …
-
Mechanistic Investigations of Taxadiene Biosynthesis Using Substrate and Transition State Analogs
… of TS and as an active site probe in X-ray crystallography.
-
Synthesis of symmetric and asymmetric water-soluble porphyrin derivatives
… ions and their structures confirmed by NMR and X-Ray crystallography. Tetramerization of excess butanopyrrole and several aldehydes also afforded novel metallo-butanocorroles and metallo-benzocorrole. The structures of these compounds are also analysed using MS (MALDI), NMR and X-Ray …
-
Fundamental efforts for improving the sensitivity of magnetic resonance force microscopy
… structures known have been solved by either X-ray crystallography or by NMR spectroscopy. Many requirements on the sample prevent these methods from being generally applicable to biological specimens. First, since X-ray crystallography and NMR spectroscopy are techniques based on assessing the …
Page 1 of 28