Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 10 of 10 for “"woven bone"”.
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Investigations into the Ulnar Response to Mechanical Stimuli Activating Lamellar and Woven Bone Formation
Woven and lamellar bone formation can be stimulated using mechanical loading. Woven bone forms rapidly in response to damaging loading in a disorganized manner with low mineral density. In contrast, lamellar bone formation can be induced in the absence of damage, and is characterized by its slow, …
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In vivo bone formation using Adipose Derived Stromal Stem Cells. The histomorphometry of the ovine defect model
The use of stem cells to augment the healing of bone defects represents an exciting new frontier in many surgical disciplines. This thesis verified the in vitro osteogenic capability of ovine Adipose Derived Stromal Stem Cells (ADSCs) and Bone Marrow Derived Stem Cells (BMSCs), examined the in vivo …
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Design and Application of Chitosan/biphasic Calcium Phosphate Porous Scaffolds for Bone Tissue Engineering
… in the defect area and subsequently enhanced new bone formation. Although the rate and extent of bone formation was similar in bFGF group to those in empty defects for the period of the study, existence of woven bone in bFGF group suggests that bone formation is continuing while the lamellar …
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The Role of Bisphosphonates and Osteoblast Lineage Cells in Promoting Osteogenic and Angiogenic Processes Necessary for Bone Repair
<p>Bone is a dynamic organ that readily undergoes bone formation and remodeling in response to its mechanical environment. This response is accelerated during injury such as full fracture and or stress fracture, where woven bone must rapidly form for successful repair and restoration of mechanical …
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Tibial bone properties and mechanics under atypical loading conditions
… to a stress fracture. The response of bone to atypical loading conditions has been less studied and can help identify conditions that may place bone at increased risk of stress fractures. Therefore, the aim of this thesis was to (1) evaluate impact strength following fatigue loading of …
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Cellular Responses to Short-Term Mechanical Loading: Relative Involvement of Osteoblasts, Pre-Osteoblasts, and Osteoprogenitor Cells
Bone is an organ that is highly sensitive to changes in its mechanical loading environment. Although it is known that increased mechanical loading results in new bone formation, the cellular mechanisms underlying this response remain unclear. This investigation applied in vivo and in vitro …
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Multi-scale characterization of swine femoral cortical bone and long bone defect repair by regeneration
… of structure and mechanical properties of bone as a function of age and regeneration of bone in long bone critical sized defects. In the first part of this study, a multi-scale experimental work was carried out to characterize cortical bone as a heterogeneous material with hierarchical …
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Octacalcium Phosphate - Metabolite Composites: model compounds for bone mineral structure
Bone turnover has important impacts on bone health. The process modifies weak primary woven bone into the strong lamellar bone, repairs damage in bone, and maintains appropriate calcium homeostasis. The process relies heavily on controlled osteoclastic resorption by dissolution of mineral in the …
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Effect of fatigue loading on impact response of rat ulna
… of both fatigue and impact loading of the bone that will potentially threat athletes’ careers. Scientists and engineers have studied the fatigue properties of many engineering materials, and more recently biological materials. Investigating the role of fatigue on impact properties has …
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The Role of Gene Transcription and Inflammatory Cytokines in Bone Fracture Repair
… will heal through either intramembranous bone formation, involving the direct formation of bone callus, or endochondral bone formation, featuring a cartilage intermediary prior to bone callus formation. Both processes begin with inflammation, which sets the stage for a successful repair …