Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 47 for “"widefield"”.
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Initial exploration of 21-cm cosmology with imaging and power spectra from the Murchison Widefield Array
The Murchison Widefield Array (MWA) is a new low-frequency radio array under construction in Western Australia with a primary goal of measuring the power spectrum of the 21-cm signal from neutral hydrogen during the Epoch of Reionization (EoR). In this thesis, we detail efforts to characterize the …
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A matched filter technique for slow radio transient detection and first demonstration with the Murchison Widefield Array
… relatively unexplored. Blind surveys with new widefield radio instruments are filling this gap. Although many of these instruments are limited by the classical confusion noise, one can in principle detect transients below the classical confusion limit. This thesis develops a technique for …
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High throughput 3D optical microscopy : from image cytometry to endomicroscopy
… for medical and biological applications based on widefield 3D resolved techniques. First, we developed a high throughput depth resolved widefield image cytometer based on the structured light illumination and the high speed remote depth scanning. This system improves imaging throughput by an order …
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Development of a Platform for Surface Enhanced Raman Scattering Endoscopy
… screening, but rather by fast large-area widefield imaging, 3) results from widefield quantitative, multiplexed SERS imaging in-vivo using phantom models, 4) the first reported study showing widefield SERS imaging of antibody-targeted SERS nanoparticles in a murine xenograft tumour model …
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New optical techniques and hardware for studying live cell dynamics
… work shows the first use of LEDs to carry out widefield axial super-resolution standing wave microscopy with high temporal resolution. The technique was used to image red blood cell membrane dynamics in real time with no increase in photobleaching or toxicity rates compared to standard …
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Multispectral optical imaging for the detection and delineation of oral neoplasia
… to high morbidity and mortality. Multispectral widefield optical imaging has emerged as a promising technology to aid clinicians in screening and resection of oral neoplasia, but current approaches rely on subjective interpretation. This work focuses on the design, construction, and clinical …
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Exploring retinal changes in Dementia and Multiple Sclerosis
… eye imaging and testing modalities such as ultra-widefield laser scanning ophthalmoscopy imaging (UWFI), adaptive optics (AO) and widefield perimetry combined with recently developed image analysis methods and algorithms. <br/><br/><br/>In this thesis I present evidences that there are detectable …
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Charge carrier transport and recombination in semiconductors: Insights from statistical analysis and machine learning techniques
… and beyond. In Chapter 6, focused and widefield excitations are compared for obtaining local TRPL data and photoluminescence intensity maps in different semiconductor materials. Widefield excitation with confocal collection emerges as the preferred approach for materials with longer …
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Computational image analysis of subcellular dynamics in time-lapse fluorescence microscopy
… algorithms on a different cell line, under both widefield and confocal microscope conditions.
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Pulsed Magnetic Imaging of Broad-Frequency Fields using Nitrogen-Vacancy Centers in Diamond
… troubleshooting. These quantum sensors yield widefield-of-view images with micron-scale spatial resolution and operate in ambient conditions. Most of the sensing work with NV centers in diamond has focused on DC and low frequency AC fields. This thesis demonstrates a wide-field magnetic imager …
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Behavioral Strategies and Neural Mechanisms of Dynamic Foraging
… of state-space behavioral modeling, large-scale widefield and single-cell imaging technologies, together with encoding models of neural responses, we showed and quantified the rich behavioral repertoire of rodents, state-dependent cortical processing of trial outcome, and diverse, distributed …
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Smart microscopy methods for quantitative microbiology
… bacterial behaviour, growth, and interaction. Widefield fluorescence microscopy, in particular, has revolutionised this field by enabling high-throughput, non-invasive, time-lapse observations of cellular processes at the single-cell level. However, despite its power, this method is not without …
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Large-Scale Characterization of Quantum Emitters in High-Purity Diamond
… of both emitters. We then demonstrate widefield photoluminescence excitation microscopy as a tool to multiplex the characterization of color center optical properties, and apply it to measure the optical properties of silicon vacancies in a sample implanted with a focused ion beam. …
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Cell engineering of human bone monolayers and the effect of growth factors and microcontact printed ECM proteins on wound healing. The role of ECM proteins, TGF¿-1, 2 and 3 and HCl/BSA in cellular adhesion, wound healing and imaging of the cell surface interface with the widefield surface plasmon microscope.
Bone repair is modulated by different stimuli. There is evidence that the Transforming Growth Factor-beta (TGF-¿) super-family of cytokines have significant effects on bone structure by regulating the replication and differentiation of chondrocytes, osteoblasts and osteoclasts. There is also …
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Compressed fluorescence lifetime imaging microscope
… referred to as compressed FLIM, can capture a widefield lifetime image of 500 450 pixels within a single camera snapshot and operate real-time two-dimensional (2D) FLIM at 100 fps. By combining compressed ultrafast photography (CUP) with FLIM and adopting dual-camera detection, compressed …
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Chasing ancient demons : tools for measuring 21 cm fluctuations before reionization
… pre-reionization fluctuations with the Murchison Widefield Array. We also use these measurements to explore the impact of low-frequency systematics, such as increased foreground brightness and the ionosphere. We discover that contamination by fine-scale frequency structure introduced by the …
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It's always darkest before the cosmic dawn : early results from novel tools and telescopes for 21 cm cosmology
… current generation telescopes like the Murchison Widefield Array, and look forward to what we might measure with the next generation of 21 cm observatories. I focus in particular on estimating the power spectrum of 21 cm brightness temperature fluctuations in the presence enormous astrophysical …
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Tools, techniques, and early results in studies of 21 cm, Lyman-alpha, and H-alpha emission from the cosmic dawn
… dynamic range antenna response of the Murchison Widefield Array (MWA) and the Hydrogen Epoch of Reionization Array (HERA). We study deviations from numerical electromagnetic models and variation among the 128 MWA antenna elements, and show both effects severely limit foreground subtraction in the …
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Graphene Microelectrode Arrays to Combine Electrophysiology with Fluorescence Imaging of Amyloid Proteins
… from cultured neurons to be combined with widefield, confocal fluorescence and fluorescence lifetime imaging microscopy (FLIM). Combining fluorescence imaging and electrophysiology will allow amyloid aggregation to be correlated with neuronal firing patterns. Another physical technique used …
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Advanced functional and intraoperative ophthalmic optical coherence tomography imaging
… ultrahigh speed enables acquisition of dense, widefield data sets as well as rapid volume acquisition to generate 3D visualizations in time. These data sets will enable 3D planning of procedures, assessment of outcomes before leaving the operating room, and feedback for surgical procedures.
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