Global ETD Search
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Showing 1 to 4 of 4 for “"whole genome alignment"”.
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Two Problems in Computational Genomics
… field of computational genomics. The first is whole genome alignment and the second is inferring horizontal gene transfer using posets. We define these two problems and present algorithmic approaches for solving them. For the whole genome alignment, we define alignment graphs for representing …
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Whole Genome Analysis of Escherichia coli and Pseudomonas aeruginosa Mixed Culture Biofilms Grown for 117 Days in Spaceflight
… 19 spaceflight isolates were chosen to undergo whole genome sequencing to be compared to the ancestral strain genomes. Illumina and Nanopore reads were used obtain draft genomes via a hybrid assembly. Whole genome alignment was used to identify differences, including SNPs, amongst the …
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Establishing a Trustworthy First Approximation for Evolutionary Distances
… have generated a large number of complete genomes. Traditionally, phylogenetic analysis relies on alignments of orthologs, but defining orthologs and separating them from paralogs is a complex task that may not always be suited to the large datasets of the future. An alternative to …
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New insights into Transposable Elements from high quality genome sequences across diverse animals
New high quality genomes, together with faster whole genome alignment methods, have opened the possibility of identifying new transposable element (TE) families by their polymorphic character in different haplotypes, in contrast to previous methods based on repetitiveness, homology and structural …