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Showing 1 to 20 of 116 for “"west nile virus"”.
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Long-term Consequences of West Nile Virus in Virginia.
… to the Virginia Department of Health with West Nile virus (WNV) non-neuroinvasive and neuroinvasive disease. The study identified the duration of symptoms after initial illness, the number of persons who fully recovered versus the number who continue to be symptomatic and how patients' …
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Molecular epidemiology of West Nile virus in North America
The introduction of West Nile virus (WNV) into the U.S. during the summer of 1999 led to the largest epidemic of arboviral encephalitis ever recorded in the Western Hemisphere during 2002. Over the course of six years, the distribution of WNV has expanded to include each of the contiguous U.S. …
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Mutational analysis of the West Nile Virus NS4B protein
West Nile virus (WNV) is a member of the genus Flavivirus in the family Flaviviridae. The WNV genome is a positive-sense RNA molecule approximately 11kb in length encoding a single polyprotein that is cleaved by a combination of viral and host proteases to produce three structural and seven …
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West Nile Virus Vaccination: Current Threats and Future Considerations
The potential role of vaccination of West Nile virus in the future and the public health logistics that may be involved.
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West Nile virus in Italy: beyond the bird routes
Context: West Nile virus (WNV) is an arthropod-borne virus considered a One Health challenge because of its increasing impact on human and animal health. It is one the most widely distributed viruses of the encephalitic Flaviviruses. It may cause severe neurological symptoms in humans and animals …
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The Molecular Epidemiology of West Nile Virus in North America
West Nile virus (WNV) was introduced into North America in 1999. The original genotype of WNV in North America, NY99, was displaced in 2002 with the current dominant genotype, NA/WN02, which was first identified in 2002. This genotype is characterized by 13 nucleotide changes encoding for one amino …
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Intrinsic Flexibility of West Nile Virus Protease: In Solution Characterization
West Nile virus (WNV) is a mosquito-borne flavivirus with a rapidly expanding global distribution. Infection can cause severe neurological disease and fatalities in humans. Efforts are ongoing to develop antiviral drugs that inhibit the WNV protease, a viral enzyme required for polyprotein …
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Secondary Transmission Dynamics of the West Nile Virus in Mosquitoes
West Nile Virus (WNV) is a member of the genus Flavivirus and is transmitted by mosquitoes. It first appeared in North America in New York City in 1999 and was first detected in Windsor Ontario in an infected bird collected in early August 2001. Prior to WNV, flaviviruses were not of major concern …
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Development of West Nile virus candidate vaccines in Nicotiana benthamiana
West Nile virus (WNV) is a widely disseminated flavivirus, with a geographical range that now includes Africa, America, Europe, the Middle East, West Asia and Australia. The virus is vectored by Culex mosquitoes and is maintained in a bird-mosquito transmission cycle with hundreds of bird species …
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Modeling, Dynamics and Optimal Control of West Nile Virus with Seasonality
West Nile virus (WNv) is a mosquito-borne disease which arrived in Canada in 2001. It has kept spreading across the country and still remains a threat to public health. In this dissertation, we formulate dynamical models and apply theory of dynamical systems to investigate the behavior of the …
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Mosquitoes, West Nile Virus, Attractants, Competition, Environmental Conditions, and Insecticide Resistance
… of this project were: 1) test for levels of West Nile Virus in mosquitoes collected at a Fulton County Recreational Facility, 2) assay various mosquito oviposition attractants on West Nile virus positive female mosquitoes, 3) test effects of distance between mosquito infusion attractants, 4) …
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Anti-Insect Defensive Behaviors of Equines after West Nile Virus Infection
West Nile Virus is an important arbovirus (virus transmitted by arthropods) that has recently affected the health of both humans and animals in the United States. West Nile fever was first identified in the US in 1999. West Nile virus (WNV), vectored by mosquitoes, has had a detrimental impact on …
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Mosquitos Associated with Equine West Nile Virus Cases in Southeastern Georgia
… associated with equine and avian cases of West Nile Virus infections in five counties in southeastern Georgia were sampled in 2003 and 2004. More than 10,500 mosquitoes representing over 20 species were collected at 25 sites using light traps and vacuum aspirators. Of these, 8,500 …
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Eco-epidemiology of West Nile virus in the midwestern United States
… invasive organisms on our planet. In 1999, West Nile virus (WNV) arrived in New York City and caused a local outbreak affecting birds and humans. In four years, the virus reached California and was present in nearly every state. Two decades later, WNV is now the most important mosquito-borne …
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West Nile virus vaccination protects against Usutu virus disease in mice
Mosquito-borne viruses, including dengue virus (DENV), Usutu virus (USUV), West Nile virus (WNV), and Japanese encephalitis virus (JEV), are rapidly emerging, global pathogens. Though the number of people impacted by each virus varies, there have been thousands to millions of people infected. The …
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Epidemiology and clinical investigation of West Nile Virus encephalitis in Houston, Texas
In 2002, West Nile virus (WNV) appeared in Houston. Retrospective medical chart reviews were completed for 172 WNV cases hospitalized in the Houston area between 2002 and 2004; 113 had encephalitis (including 17 fatal cases), 47 had meningitis, and 12 were uncomplicated fever cases. Risk factors …
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Statistical Modelling of Mosquito Abundance and West Nile Virus Risk with Weather Conditions
… of mosquito-borne infectious diseases such as West Nile virus (WNv). Study and prediction of these effects could be used to develop disease forecasting methods. In this dissertation, we analyzed the frequency distribution of mosquito surveillance data and built the statistical forecasting …
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MyD88-Mediated Signaling in Protective Immunity against an Attenuated West Nile Virus Infection
West Nile virus (WNV) nonstructural (NS) 4B-P38G mutant is highly attenuated in mice. Interestingly, it induces strong immune responses and protects mice from subsequent lethal wild-type WNV NY99 infection. These features have important applications in flavivirus vaccine development. The goal of my …
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Phenotypic Characterization of Mutations Made to the Envelope Protein of West Nile Virus
West Nile virus (WNV) is a mosquito-borne flavivirus that can cause severe neuroinvasive disease resulting in death or long term neurological sequela. The envelope (E) protein of flaviviruses has three domains and is the major component of the virion surface, with the EIII being the putative …
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