Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 87 for “"water maze"”.
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Water Maze Strategies used by Mice Exposed to Radiation and Pomegranate Juice
… learning that is easy to study in animals. The water maze is a test that requires the animal to use spatial navigation skills to find a submerged (hidden) platform in a pool of water. Disease and injury that affect the hippocampus result in spatial learning deficits and altered search strategies …
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A Behavioural, Molecular and Lesion Examination of Hippocampal Contributions to Morris Water Maze Acquisition
The Morris water maze (MWM) is a widely known, simple and effective task in the examination of spatial learning and memory. Successful acquisition of the task is thought to rely on retained representations of allocentric spatial relations, whereby animals learn to associate the location of a hidden …
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Gender Differences in Working Memory in Humans Tested on a Virtual Morris Water Maze.
<p>A computerized virtual version of the Morris water maze (vMWM) was used to assess human gender differences in spatial working memory. In Experiment 1, the release point and platform location was changed on every other trial for 20 trials. Men had significantly reduced acquisition latencies and …
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An Examination of the Influence of Landmarks in Human Spatial Navigation Using a Virtual Water Maze
… excelled with the invention of the Morris Water Maze (Morris, 1984). In this task animals are required to find a platform, hidden somewhere in a large circular pool of water (below surface level). As animals cannot see the goal directly, they must use various cues in the environment to …
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Age sensitivity of the Barnes Maze and the Morris Water Maze: Associations with cerebellar cortical Purkinje neurons
… substrates as assessed by the Morris water maze (MWM) and the Barnes maze. The MWM is one of the most widely used tests of spatial memory and numerous studies suggest that spatial memory abilities decline with age. To contrast, very few studies exist comparing different ages of mice in …
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A Multi-Region Analysis of the Acquisition, Consolidation and Retention of Spatial Memory in the Morris Water Maze using Immediate Early Gene Imaging
The Morris water maze has been extensively used in the study of spatial learning and memory, and a number of hippocampal, parahippocampal and neocortical brain regions have been identified as necessary for successful performance in this task. Immediate Early Genes (IEGs) have been implicated in …
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An Analysis Of Virtual Place Learning/navigation In Children And Young Adults Prenatally Exposed To Alcohol
… exposure impairs performance on the Morris water maze. This task requires the rodent to use distal room cues to locate a hidden platform in a pool of opaque water. Successful performance on this task is dependent upon hippocampal function. Rodents prenatally exposed to alcohol are impaired …
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Efeito da administração crônica pós-natal dos ácidos propiônico e metilmalônico sobre o comportamento de ratos no labirinto aquático de Morris (Water Maze) e sobre alguns parâmetros bioquímicos de estresse oxidativo em hipocampo
As acidemias propiônica e metilmalônica são desordens neurometabólicas hereditárias caracterizadas por progressiva deterioração neurológica, retardo mental, atraso no desenvolvimento psicomotor, convulsões e coma. A fisiopatologia do dano cerebral característico destas doenças ainda é pouco …
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Behaviorally-Induced Structural Remodeling of the Hippocampus
… after completion of spatial learning. Water maze training is a spatial learning task that requires the animal to use distal cues to locate a platform hidden two centimeters below the water. Rats with a higher density of mossy fiber growth were expected to spend more time in the correct …
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An Examination of Hippocampal and Prefrontal Contributions to Spatial Learning and Memory using Immediate Early Gene Imaging
… these areas continue to be debated. The Morris water maze is a well-known behavioural task used to measure spatial memory. Despite its popularity, the type of spatial information animals encode and ultimately rely on for accurate navigation in this task remains unclear. Therefore, the primary …
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The Mouse Magnetic Compass
… field to position their nests and to solve a water maze task. The primary objective of this research was to characterize the magnetic compass of C57BL/6 laboratory mice in the plus water maze task. These experiments explored sources of variation in magnetic responses and investigated the …
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Traumatic Brain Injury Accelerates Alzheimer’s Disease Pathology in the TgF344-AD Rat Model
… post-injury days 1-3 and 3 months after injury. Water maze test was performed 3 months after Injury, then rats were sacrificed, and the brains were removed for immunohistological analyses of Aβ, p-Tau, and neuroinflammation. Results: TBI TgF344-AD rats performed significantly worse in the beam …
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Mixed Dementia Induced by Right Common Carotid Artery Occlusion in an Alzheimer Mouse Model
… carotid artery occlusion (rCCAO). The Morris water maze and object recognition tests were performed 6-8 weeks after the operation; the mice were then sacrificed. We evaluated cell death by histological studies and quantified the amount of amyloid plaques. An escape performance in the Morris …
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Confidence Intervals for the Difference and Ratio of Two Means from Independent Beta Distribution
… be applied to real biological data from a Morris Water Maze experiment, with recommendations for best practices.</p>
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Age-related differences in ethanol withdrawal, withdrawal-induced anxiety, cognition, and response to allopregnanolone.
… behavior and hyperactivity in the elevated plus maze and open field tasks during withdrawal. In contrast, aged animals consumed significantly less ethanol per body weight than adults and achieved minimal withdrawal scores using the standardized scale, but exhibited profound anxiety-like behavior …
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The role of the CB1 receptor in learning, memory and anxiety-like behaviors
… between CB1+/+ and CB1-/- mice in a Morris Water Maze acquisition task. Furthermore, CB1-/- mice did not display deficits in extinction during reversal learning. In the Light-Dark Box and Suok tasks, the CB1-/- mice demonstrated greater anxiety-like behaviors relative the CB1+/+ mice. No …
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The role of the CB1 receptor in learning, memory and anxiety-like behaviors
… between CB1+/+ and CB1-/- mice in a Morris Water Maze acquisition task. Furthermore, CB1-/- mice did not display deficits in extinction during reversal learning. In the Light-Dark Box and Suok tasks, the CB1-/- mice demonstrated greater anxiety-like behaviors relative the CB1+/+ mice. No …
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Cognitive Mechanisms of Memory Impairment Following Traumatic Brain Injury
… to a pre-determined criterion in a 1 -day water maze procedure.Although injured animals required more trials to reach criterion, the rate of forgetting was identical among sham and injured groups up to 24hrs post-training. This suggests that the amount of information encoded into long-term …
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Environmental- and Ethanol-Induced Effects on Reference and Short-Term Memory in the Rat
… short-term memory, as assessed in the radial arm water maze (RAWM) and Morris water maze (MWM). Sprague-Dawley rats (N=18) were exposed to either EE or isolation for 4 hours/day for 4 weeks prior to and during the experiments. Animals were first trained and tested with non-spatial cues located at …
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The effects of acute stress on retrieval of visual and spatial material
… impaired memory retrieval, as demonstrated by water maze performance, in rodents. To replicate their design for use in humans, I needed to make several apparatus substitutions. Hence, before embarking on the major studies that constitute the dissertation, I undertook two pilot/preparation …
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