Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 5 of 5 for “"volumetric muscle loss"”.
-
Naturally Derived Scaffolds for Treatment of Volumetric Muscle Loss
Volumetric muscle loss (VML) is defined as the irrecoverable loss of function in skeletal muscle as a result of tissue loss. Herein, cell and growth factor loaded keratin hydrogels and Tissue Engineered Muscle Repair (TEMR) constructs consisting of cell seeded, cyclic stretched bladder acellular …
-
Development and Characterization of Tunable, Bioinspired Electrospun Constructs for Skeletal Muscle Engineering
Volumetric muscle loss, as a result of high intensity sports injury, trauma or tumor ablation, affects more than 250,000 civilians each year in the U.S. alone and accounts for more than 50% of all DoD disabilities. These injuries often leave patients with permanent structural and functional …
-
THE ROLE OF INNERVATION IN ENGINEERED MUSCLE
Skeletal muscle injuries span a wide spectrum, from minor strains to devastating traumatic events, and represent a significant clinical challenge worldwide. Millions of individuals experience severe muscle deficits each year, including volumetric muscle loss (VML) resulting from ballistic trauma, …
-
DEVELOPMENT OF A TISSUE ENGINEERED SKELETAL MUSCLE REPAIR CONSTRUCT FEATURING BIOMIMETIC PHYSICAL, CHEMICAL, AND MECHANICAL CUES
Volumetric muscle loss (VML) injuries are particularly debilitating, and commonly result from trauma, infection, congenital defect, or surgical side effect. Unfortunately, current medical treatments for these injuries are lacking. The "gold standard" for treatment of critical-size defects remains …
-
Investigating the Impact of Biochemical and Mechanical Stimuli on Motor Neuron Growth
… promote reinnervation and angiogensis in a rat volumetric muscle loss model. Our study queried the individual effects of biochemical and mechanical stimuli on neuronal growth to push the field of neuromuscular systems forward. We utilized optogenetic stimulation to emulate the biochemical …