Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 15 of 15 for “"volume regulation"”.
-
Astrocyte volume regulation during aging
Astrocyty, ako jeden z druhov gliových buniek, hrajú dôležitú úlohu v zdravo fungujúcej centrálnej nervovej sústave, ale takisto aj v jej patológii. Keďže jedna z ich funkcií je udržiavanie iónovej, neurotransmiterovej a vodnej homeostázy, astrocyty majú schopnosť regulovať svoj objem. Hypo- a …
-
Homeostasis and volume regulation in the Plasmodium falciparum infected red blood cell
… of the parasite asexual reproduction cycle. The volume and shape changes of infected cells were measured and characterized at femtolitre resolution throughout the intraerythrocytic cycle using confocal microscopy. Fluorescence lifetime imaging and electron probe X-ray microanalysis were applied …
-
Glutamate Receptor-Mediated Taurine Release From The Hippocampus During Oxidative Stress
… edema in vitro. Swollen brain cells activate volume regulatory mechanisms including a significant efflux of the endogenous sulfonic amino acid taurine via volume-regulated anion channels (VRACs). Studies in brain slice preparations also suggest that the excitatory amino acid glutamate plays an …
-
Regulation of Volume by Spermatozoa and Its Significance for Conservation Biology
… reproductive technologies. Investigation of the volume regulatory mechanism of spermatozoa could produce options to improve the cryopreservation of spermatozoa and provide a non-hormonal contraceptive option for men, both of which could have significant impacts on global biodiversity …
-
Effects of salinity stress, ammonia exposure and feeding on excretory nitrogen metabolism in the marble goby, oxyeleotris marmorata
… O. marmorata exhibited hyperosmotic hyperionic regulation in freshwater, but undergo hypoosmotic hypoionic regulation during seawater exposure. Short-term seawater exposure resulted in cell volume regulation partially achieved by using FAAs as osmolytes. Long-term seawater exposure resulted in …
-
K(ATP) channel Kir62 subunit distribution differs between muscles and between fiber types in skeletal muscle
… channel has been shown to be involved in cell volume regulation, modulation of glucose uptake, and the prevention of fiber damage and contractile dysfunction during fatigue. The extent of the cytoprotective capabilities of the KATP channel vary tremendously between muscles with different muscle …
-
Fluidic Flexible Matrix Composite Wafers for Volume Management in Prosthetic Sockets
… knee) prostheses experience changes in the volume of their residual limb during the course of the day. These changes in volume unavoidably lead to changes in quality of fit of the prosthesis, skin irritations, and soft tissue injuries. The associated pain and discomfort can become …
-
Excretory nitrogen metabolism in the Chinese soft-shelled turtle, pelodiscus sinensis
… were accumulated in various tissues for cell volume regulation with accumulations facilitated by increases in proteolysis and catabolism of certain amino acids respectively. Consequently, the rate of urea synthesis increased 1.4-fold. During 6 days of emersion, turtles maintain levels of …
-
Life Under Tension: Computational Studies of Proteins Involved in Mechanotransduction
… muscles and bones to sound transduction and cell volume regulation, handling of forces is essential to life. Investigation of the microscopic machinery behind force generation and transduction in the cell has only become possible with recent advances in x-ray crystallography, nuclear magnetic …
-
Dynamic Properties of Chondrocytes
… mechanical loading in vivo and adapt their volume and shape accordingly, a process that is essential for maintaining cartilage health and function. Volume and shape changes in chondrocytes are key to cellular mechanotransduction, the mechanism by which cells detect and respond to external …
-
Mechanisms of ion channel activation in primary cultured and clonal cell lines
… primary cultured calvarial osteoblasts. The volume-sensitive Cl- current in ROS 17/2.8 cells was inhibited by arachidonic acid in two distinct phases. A rapid block that developed within 10 s, preceding a slower developing inhibitory phase that occurred approximately 90 s after onset of …
-
Sphingosine-1-Phosphate and Fingolimod (FTY720) Regulate ICl,swell In HL-1 Cardiac Myocytes via Intracellular Binding And Mitochondrial ROS Production
… role in cardiac electrical activity, cellular volume regulation, apoptosis, and acts as a potential effector of mechanoelectrical feedback. Persistent activation of ICl,swell has been observed in models of cardiovascular disease. We previously suggested sphingosine-1-phosphate (S1P) activates …
-
Characterizing Changes in the Brain During Hydrocephalic Development and Exploring Potential Treatment Strategies
… cells contribute to brain fluid/electrolyte regulation and barrier integrity. Increased glial fibrillary acidic protein (GFAP) fluorescence, a marker of activated astrocytes, appeared in hydrocephalic (Tmem67-/-) animals by immunohistochemistry as early as postnatal day (P)10. The tight …
-
Die Regulation des Na+2Cl-K+-Cotransporters in der basolateralen Membran der Rattenkolonkrypte
Mit der vorliegenden Arbeit wurde die Regulation des Na+2Cl-K+-Cotransporters in der basolateralen Membran der Rattenkolonkrypte untersucht. <br>Dazu wurde die NH3/NH4+-Puls Technik zusammen mit der BCECF-Fluoreszenzmessung verwendet. Dabei stellt die langsame Azidifizierung des Zytosols in der …
-
Die Rolle von Kalium- und nichtselektiven Kationenkanälen der Kolonkrypte der Ratte bei Zellschrumpfung
In Untersuchungen mit der Saugelektrodentechnik sind an kultivierten M1-Zellen des kortikalen Sammelrohrs eine nichtselektive Kationenleitfähigkeit bzw. Einzelkanäle beobachtet worden, die bei Erhöhung der extrazellulären Osmolorität aktiviert wurden. An Kolonkryptzellen der Ratte sind …