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Showing 1 to 3 of 3 for “"voltage-gated Na+ channels"”.

  1. Protein modulators of voltage-gated Na+channels and γ-aminobutyric acid type a receptors

    Gonzalez-Prada Felices, Jose EnriqueUniversity of Cambridge2025

    [Restricted]

    cambridge Repository record

  2. The Mechanism of Action of Lidocaine and Levobupivacaine on Human Cardiac Voltage-gated Na<sup>+ </sup>Channels Na<sub>V</sub>1.5

    Elajnef, Taha RasemUniversity of Dundee2016

    Voltage-gated Na+ channels (VGSCs) in nociceptive neurons are the molecular targets for local anaesthetics. However, due to the ubiquity of VGSCs in excitable tissues, they are prone to inhibition by local anaesthetics, including the cardiac NaV1.5 subtype, which is also expressed in metastatic …

    dundee Repository record

  3. Effects of Ca2+, microRNAs, and rosuvastatin on insulin-secreting beta cell function

    Salunkhe, Vishal AshokIslet cell exocytosis, Dept of Clinical Scinces2015

    … treatment of T2D. In this thesis I have investigated the role of Ca2+, miRNAs and rosuvastatin in the regulation of ion channels, exocytosis and insulin secretion of beta cells. For this purpose, pancreatic rat INS-1 832/13 beta cells, rodent animal models, and islets from human cadaver donors …

    lund Repository record