Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 11 of 11 for “"voltage sensitive dye"”.
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Imaging räumlicher und zeitlicher Dynamik der Geruchstoffrepräsentation im Bulbus Olfactorius der Säugetiere mit einem neuen spannungsabhängigen Farbstoff
… temporal resolution. We chose the technique of voltage sensitive dye imaging (VSDI) to explore the spatio-temporal dynamics of odor-evoked activ-ity in the rat and mouse main olfactory bulb (MOB) with high temporal resolution. As established optical probes did not yield sufficient signals I …
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Modification of Aplysia Feeding Network By L-Dopa and Dopamine-Dependent Learning
… of up to 130 neurons simultaneously using a voltage-sensitive dye (RH-155). L-DOPA selected one of two distinct buccal motor patterns (BMPs): intermediate (low L-DOPA) or bite patterns (high L-DOPA). The selection of intermediate BMPs was associated with shortening of the second phase of the …
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A study of synchronization of nonlinear oscillators: Application to epileptic seizures
… in the rat neocortex are measured using voltage-sensitive dye imaging. Epileptic regions show well-synchronized, in-phase activity during epileptic seizures. In the computational part, a network of a Hodgkin-Huxley type neocortical neural model is constructed. Phase reduction, which is a …
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Distortions in Perceived Direction of Motion Predicted by Population Response in Visual Cortex
… of stimulus motion. Here I employed in vivo voltage sensitive dye (VSD) imaging to explore how abrupt changes in the trajectory of a moving stimulus impact the population coding of motion direction in ferret primary visual cortex (V1). For motion in a constant direction, the peak of the …
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Polarization-Maintaining Fiber-Based Optical Coherence Tomography on Functional Imaging in Dense Nerve
… olfactory nerve. A dual-wavelength polarization-sensitive spectral-domain OCT system has been designed and constructed in house for depth-resolved optical recordings. The olfactory nerves dissected from pike were used with or without voltage-sensitive dye staining. M-mode and cross-sectional …
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Cellular and Circuit Level Responses to Neural Stem Cell Transplantation in the Rodent Cortex
… in acute slices of somatosensory cortex using voltage sensitive dye imaging. Single and repetitive callosal stimuli elicited activity that originated in deep layers, propagated vertically along cortical columns, and spread horizontally across superficial layers. Very high levels of C17.2 …
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Investigation of the mechanisms underlying the effects of hyperglycaemia on cardiac structural and electrical remodelling
… baseline- or high glucose conditions. A Ca2+ -sensitive fluorescent dye Fluo-4 was used to measure calcium transients and a voltage-sensitive dye di-4-ANEPPS was used to record action potentials. Cellular biomarkers were detected using immunocytochemistry, confocal microscopy, and Western …
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Novel contrasts in photoacoustic tomography
… chromophores, nanoparticles, small-molecule dyes and genetically-encoded proteins. With these novel contrasts, the proof-of-concept applications of PAT have been extended to include homogenous flow measurements, targeted angiogenesis imaging and therapy, label-free white blood cell imaging, …
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Arrhythmia mechanisms in acute ischaemia and chronic infarction in rabbit heart
… of isolated hearts was examined using the voltage sensitive dye RH237 and optical action potentials were recorded from a 13x13mm area of left ventricular epicardium using a 16x16 element Hamamatsu photodiode array. Contraction motion artefacts were practically eliminated with blebbistatin …
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The electrophysiology of the atrioventricular node in normal and failing rabbit hearts
… optical mapping of electrical activation using voltage sensitive dye I observed that the prolongation of the AH interval is predominantly a consequence of conduction delay between the inputs of the AV node and the compact nodal region. Neuro-hormonal derangement in chronic heart failure has a …
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Analysis of The Distributed Representation of Operant Memory In Aplysia
… operant memory. Using single-neuron resolution voltage imaging and dimensionality reduction, an advancement in the recruitment of one of two motor modules was identified as the primary signature of operant learning in the population activity. The third study expanded the functional …