Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"voltage gating"”.
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Voltage-Gating Mechanism in Potassium Channels
"Voltage-gated potassium channels are membrane proteins that regulate the flow of K+ ions across the cell membrane. These channels respond to changes in electrostatic potential across the cell membrane, and allow passage of K+ ions through their conduction pore. In excitable cells, an interplay of …
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Voltage-Gating Mechanism in Potassium Channels
Voltage-gated potassium channels are membrane proteins that regulate the flow of K+ ions across the cell membrane. These channels respond to changes in electrostatic potential across the cell membrane, and allow passage of K+ ions through their conduction pore. In excitable cells, an interplay of …
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Ion transport across individual sub-continuum graphene nanopores : phenomenology, theory, and implications for industrial separations
… as well as nonlinear ionic transport such as voltage-activated and rectified current-voltage curves. Furthermore, in rare instances, nanopores exhibited real-time voltage gating where the nanopore switches between two states in a voltage-dependent manner. The set of these behaviors are in fact …
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Using Lipid Bilayers in an Artificial Axon System
… to a lipid bilayer interface due to the voltage-gating properties of alamethicin within the connected bilayer. The system was used to show a signal boosting behavior similar to what occurs in the nodes of Ranvier of a myelinated axon. In addition, the artificial axon system was used to …
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Voltage programmable materials
… interface reactions paves the way towards voltage control of these properties in solid-state devices. Here, we focus on ferromagnetic metal/metal-oxide bilayers that exhibit strong perpendicular magnetic anisotropy derived from interfacial oxygen hybridization. In these materials, we …
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Cholesterol Modulation of BK Currents and Cerebral Artery Diameter Via Channel-Forming Alpha-Subunit
<p>Voltage- and calcium-gated, large conductance potassium channels (BK; MaxiK) are ubiquitously expressed and subsequently mediate numerous physiological processes. Cholesterol is consumed in high amounts with the diet and accumulates in cellular membranes when plasma levels become elevated. …
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Computational studies of membrane proteins: Structure, function and dynamics
… channels, detailed molecular mechanisms of the gating and ion selectivity remain elusive. The main aim of this dissertation is to employ molecular dynamics simulations to investigate the structure and function of ion channels, including the gating mechanism in voltage-gated potassium and sodium …
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Molecular Basis of Mechanosensitivity
… from the MacKinnon Lab showed that certain voltage gated potassium channels, not previously associated with mechanosensation, are in fact remarkably sensitive to membrane tension in isolated membrane patches. I therefore began investigating the possibility of voltage gated potassium channels …