Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 59 for “"visual function"”.
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The Association between Obesity, Cognition, and Visual Function
… consequent to obesity, to impaired cognitive function. Obese rodent models have been established and are commonly used for obesity-related research; however, with respect to the effect of obesity on cognitive function, the data remain inconclusive. In these studies, two obese mouse models, …
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Visual Discomfort and Visual Function: Colour and Contrast
In six studies, vision and visual discomfort were investigated in individuals who experienced migraine or reading difficulty. Contrast discrimination thresholds were measured at two pedestal contrasts (10% and 50%) in volunteers with migraine with aura (MA), without aura (MO) and controls (C).There …
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Characteristics of visual function in Asperger’s syndrome and the autism spectrum
… and investigate current theories concerning visual function in individuals with Asperger’s syndrome and high functioning autism spectrum disorder and to translate the findings into clinical practice by developing a specific protocol for the eye examination of individuals of this population. • …
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Visual Function in New Zealand Children: from Preschool to Primary School
… refractive error is the leading cause of visual impairment in children and has been associated with reduced academic performance. This thesis investigated the role of the current preschool vision screening programme in detecting vision conditions, as well as the associations of vision …
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A New Model for Assessment of Change in Visual Function in Diabetes
… to interpret deterioration or improvement in the visual field can be employed to assess change in visual function over time in diabetes. Diabetic retinopathy has long been considered a microvascular disease, but it is still a matter of debate to what extent diabetes also affects retinal neurons. …
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Gene therapy provides long-term visual function in a pre-clinical model of retinitis pigmentosa
… RP present with the loss of their peripheral visual field, and the disease will progress until there is a full loss of vision. Approximately 36,000 cases of simplex and familial RP worldwide are caused by a mutation in the rod-specific cyclic guanosine monophosphate phosphodiesterase (PDE6) …
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Myopia: structural and functional correlates
… shape are then correlated with measures of visual function. Key findings include the significant homogeneity of ocular volume in the anterior eye for a range of refractive errors, whilst significant volume changes occur in the posterior eye as a function of ametropia. Anterior vs. posterior …
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Predicting Vision Loss In Healthy Aging With Manganese-Enhanced Mri Of The Rat Eye
<p>In healthy aging, visual function declines throughout adulthood. Age-related changes in neuronal ion homeostasis -- specifically, increased Ca2+ influx through L-type voltage gated calcium channels (L-VGCCs) -- are believed to contribute to certain functional declines, but this possibility has …
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Visual functioning and quality of life after pars plana vitrectomy for diabetic eye disease at Groote Schuur Hospital, Cape Town, South Africa
The purpose of this study was to determine the visual function and quality of life of patients 6 months after undergoing pars plana vitrectomy for diabetic retinopathy complications at the Groote Schuur Hospital. The study also investigated the association between quality of life and the …
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Glistenings in Intraocular lenses and their effect on forward light scatter; an in vitro study
… correlation with a number of measures of visual function. The purpose of the work reported in this thesis was to test if there was an association between in vitro forward light scatter and grade of glistenings. The in vitro approach allows measurement of forward light scatter without the …
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Knowledge Mining In The Clinical Assessment Of Glaucoma
… is a leading cause of irreversible blindness and visual impairment. In the clinic, glaucomatous damage can be characterized by structural changes in the optic nerve head (ONH) and retinal nerve fibre layer (RNFL) that can be evaluated by various retinal-imaging techniques such as scanning laser …
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Investigating quality of life in inherited optic neuropathies: Evaluating patient experiences and outcome measures
… of the optic nerve due to mitochondrial dysfunction. The two most common IONs encountered in clinical practice are autosomal dominant optic atrophy (DOA) and Leber hereditary optic neuropathy (LHON). In both conditions, visual failure typically begins in the first three decades of life, with …
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Functionally non-adaptive retinal plasticity in rat models of human retinal degenerative disease
… proposed to account for these limitations: the visual adaptation model. The visual adaptation model was developed to provide a novel approach for testing potential treatments for retinal disease, and the work in this thesis provides empirical support for this model. Specifically, we evaluated …
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Ophthalmic complications of spina bifida and hydrocephalus
… of raised intracranial pressure due to shunt dysfunction even when other objective evidence was lacking. Every spina bifida and hydrocephalus clinic should have an ophthalmalogist in its medical team. Preservation of visual function and early diagnosis of raised intracranial pressure in these …
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Discovering Dynamic Visemes
… thesis introduces a set of new, dynamic units of visual speech which are learnt using computer vision and machine learning techniques. Rather than clustering phoneme labels as is done traditionally, the visible articulators of a speaker are tracked and automatically segmented into short, visually …
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A study of the role of advanced technologies in glaucoma case-finding
… and non--‐POAG/ non--‐OHT subjects than either visual function test (Frequency Doubling Technology or Moorfields Motion Displacement Threshold). The low specificity of visual function tests precludes their use in isolation, but their use together with objective evaluation of optic nerve head …
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Structure-function relationships in Age-related macular degeneration in an era of multi-modal retinal imaging
… (AMD) is the most common cause of irreversible visual impairment in the western world. Multimodal imaging has contributed a lot into disease detection, diagnosis and management. The availability of multimodal imaging is an unprecedented advantageous opportunity into relating structure with …
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Environmentally Influenced Duplication Patterns Followed by Functional Shifts Fueling the Evolution of Metazoan Sensory Systems
… in sensory evolution by duplication followed by functional shifts resulting in neofunctionalisation has been analysed. This extensive neofunctionalisation allows for an expansion in the number of environmental signals the animal can detect. In the following chapters, some of the ways gene …
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The Development of Flash Visual Evoked Potential Techniques for the Diagnosis of Visual Disorders with Dense Opacities of the Optic Media
Visual evoked potentials (VEP)were recorded in a large normal population. Significant age differences were found, and the P2 component (latency 116 m.sec.) was the most consistent component of the VEP both between and within the individuals. The validity of the normal VEP criteria were tested in …
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Study of the Functional Role of ATP1A3A in the Vertebrate Nervous System
… found in all animal cell types. The primary functions of Na+, K+ ATPases are to maintain electrochemical gradients across cell membranes by actively transporting Na+ and K+ ions between intracellular and extracellular spaces using ATP hydrolysis. In vertebrates, Na+, K+ ATPases come in a …
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