Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"virus-host interaction"”.
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Use of an Atg16l1 mouse model to study the role played by autophagy in neuroprotection
… To investigate autophagy in the context of virus‐host interaction, Semliki Forest Virus infection was tested in Atg16l1 KO tissues. Atg16l1 KO had no effect on virus proliferation in organotypic brain slice cultures while viral nsP1 and capsid expression was reduced in Atg16l1 KO embryonic …
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Evolutionary and ecological consequences of chronic infection in Sulfolobus islandicus
… not often considered from this perspective, virus-host interactions represent a symbiotic interaction that exists along a continuum from antagonistic to mutualistic. In microbial ecology and evolution, this relationship has mostly focused on antagonistic lytic viruses. Lytic viruses are …
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Molecular Mechanism of Parvovirus Infection
… effects induced during infections of parvovirus B19 (B19V) and minute virus of canines (MVC); 2) identifying the role of EpoR signaling in supporting B19V replication in erythroid of progenitor cells. To the first part, we take advantage of a recently developed in vitro permissive B19V …
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Host Entry Factors for Human Coronaviruses
<p>Coronaviruses infect a diverse range of animals from birds to pigs and cats to humans. Coronaviruses employ RNA-based replicative processes and as such are genetically adaptable to acquire novel host ranges. A coronavirus from one species can jump to another by shifting its entry requirements. …
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Analysis of Cellular Transcriptomic Changes Induced by Merkel Cell Polyomavirus miRNA
… with rising global incidence. Merkel cell polyomavirus (MCV) was discovered in 2008 in 80% of MCC samples and since then a causal link between MCV and the majority of MCC cases has been established. microRNAs (miRNA, miR) are a family of small non-coding RNAs which play a key role in …
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The development of novel diagnostic countermeasures for Rift Valley fever virus
Rift Valley fever virus (RVFV) is a zoonotic arbovirus that is a significant threat to livestock and humans. It is listed as #3 for most dangerous animal threats and is in the top 10 pathogens needing urgent research in preventative and control measures. Although RVFV has never been reported in the …
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Arenaviruses: the Role of Antigen Presenting Cells (APC) in Persistence and Immunopathology
Viruses are major contributors to global health crises. Many of the disease pandemics the world has experienced were caused by viruses from smallpox to Spanish flu, Ebola (Public health emergency of international concern), SARS, West Nile, Zika and currently SARS-CoV-2 the aetiology of COVID19. At …
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Characteristics of an Endonuclease Associated with Adenovirus Types 2 and 12
<p>Adenovirus type 2 productively infects human cells and hamster cells. Adenovirus type 12 productively infects human cells but abortively infects hamster cells. The metabolism of the DNA of these adenoviruses was determined in both human cells and hamster cells. The adenovirus DNA, both the …