Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 11 of 11 for “"virus neutralization"”.
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Effects of variation in N-linked glycosylation site on antibody mediated neutralization in PRRSV
Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) is a 15Kb enveloped positive-sense, single stranded RNA virus. More than two decades after the emergence of PRRSV, much is known about the viral genome, spread, and pathogenesis of the disease but our knowledge of the protective immune …
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Evolution-dependent SARS-CoV-2 vaccination success determined by neutralizing antibodies and reliability of point-of-care testing
… BA.2. Moreover, we established a Vero cell-based virus neutralization test to validate various diagnostic systems and to estimate vaccination success. Since RT-qPCR tests were not sufficient for mass testing, point-of-care tests (POCTs) for antigen detection became necessary. In 2020, we …
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Surveillance of Emerging Livestock Viruses
… severe outbreaks of porcine epidemic diarrhea virus (PEDV) in Asia and North America highlighted the need for well-validated diagnostic tests for identification of PEDV infected animals and evaluation of their immune status. PEDV was first detected in the U.S. in May 2013 and another swine …
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Development of novel Competitive Enzyme-linked immunosorbent assays to detect SARS-CoV-2-specific antibodies in animals
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the COVID-19-causing virus, is a zoonotic pathogen. There is concern about the virus spilling over from humans into wildlife species, which may then serve as reservoirs for future infection of humans and other animals. Furthermore, the …
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Field comparison of intranasal and injectable bovine respiratory disease vaccination on beef calf antibody concentrations, average daily gain, and bovine respiratory disease morbidity
… with an ELISA for bovine respiratory syncytial virus (BRSV) and bovine herpes virus type 1 and virus neutralization for bovine viral diarrhea virus types 1 and 2. No differences were observed between the average daily gains of the three groups. The IN-KV group had significantly higher BRSV …
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Vaccine Development Against Porcine Epidemic Diarrhea Virus Utilizing the Hepatitis B Virus Core Antigen Protein
Porcine epidemic diarrhea Virus (PEDV) is a virus effecting swine. It is the cause of disease that manifests with symptoms ranging from depression, to severe dehydration and death. Young piglets are particularly susceptible to the virus, which can reach mortality rates of 100%. Presence of the …
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Modeling dengue viral infection, insect transmission and multiplex PCR in humanized mice
Due to the restricted host specificity of dengue virus, up until now no ideal animal model has sufficiently mimicked key aspects of viral pathogenesis and immune response. In this regard, new advances with humanized mice(hu-mice), constructed by engrafting human tissues and cells and harboring a …
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Development of plant-produced African horse sickness vaccines
… is caused by nine different serotypes of the orbivirus African horse sickness virus (AHSV) and it is spread by Culicoid midges. The disease has significant economic consequences for the equine industry both in southern Africa and increasingly further afield as the geographic distribution of the …
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Bindung von Hepatitis C Virus-ähnlichen Partikeln an Zielzellen : ein Modell zur funktionellen Untersuchung von antiviralen Antikörpern
… zum HCC fortschreiten kann. Die Bedeutung von Virus-neutralisierenden Antikörpern für die Viruselimination ist durch das Fehlen von effizienten Modellsystemen zur Virusneutralisation nur unvollständig verstanden. Wir haben kürzlich gezeigt, dass die Expression der HCV-Strukturproteine in …
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The development of a novel vaccine against avian influenza H7N9 virus
Influenza A viruses (IAV) are classified into the Orthomyxoviridae family and are composed of segmented, negative-sense, single-stranded ribonucleic acid (ssRNA) genomes in an enveloped particle. IAV is capable of infecting a wide variety of species, including but not limited to humans, birds, …
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Interaction of the porcine reproductive and respiratory syndrome virus with the macrophage-specific lectin sialoadhesin
The porcine reproductive and respiratory syndrome virus (PRRSV) causes the economically most important viral disease in swine industry today. The virus is a major threat to swine health worldwide, since it is both associated with the porcine respiratory disease complex and the cause of severe …