Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"virus lifecycle"”.
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Exploring the roles of key lipids in the influenza virus lifecycle
The influenza virus is a common respiratory pathogen with the capacity to cause global pandemics affecting millions of people, contributing substantially to overall mortality and morbidity. Thus, considerable research focuses on the prevention and treatment of influenza virus infection. Despite the …
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Adenosine triphosphate is an allosteric inhibitor of coxsackievirus B3 3Dpol
Picornaviruses pose a significant threat to human and animal health, but at present there are no drugs to prevent or treat picornaviral infections. However, intensive study of the picornaviral lifecycle has revealed several promising pharmacological targets, including the RNA-dependent RNA …
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MIR-122 and DDX6 facilitate hepatitis C virus replication via independent mechanisms
… 130 million people are infected with hepatitis C virus (HCV) that leads to chronic hepatitis. Current therapy is limited in its efficacy; hence better interventions are required. A detailed understanding of the host factors involved in HCV replication such as miR-122 and DEAD-box RNA helicase, …
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NEW INSIGHTS INTO THE MOLECULAR PATHOGENESIS OF SEVERE FEVER WITH THROMBOCYTOPENIA SYNDROME VIRUS
… Fever with Thrombocytopenia Syndrome (SFTS) virus (also known as Dabie Bandavirus) is an emergent tick-borne Phlebovirus isolated from patients presenting with hemorrhagic manifestations. Case fatality rates range from 12-50%, and over 1 billion people live in regions where the virus is …
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Dissecting Host-Viral Interactons Through Focused or Unbiased High-Throughput Genetic Approaches
<p>In the world around us, viruses surround and vastly outnumber us. Indeed, there are roughly 1 sextillion—or one thousand million million million—times as many viral particles as humans on earth (1). While most of these viruses do not cause disease in humans, those that do present a grave and …