Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 321 for “"virulence factors"”.
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Virulence factors in non-gastric Helicobacters
Thesis (S.M.)--Massachusetts Institute of Technology, Division of Toxicology, 1998.
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Genomics and virulence factors of Fusobacterium necrophorum
… genome and identify and study its putative virulence factors contained using in silico and in vitro analysis. Type strains JCM 3718 and JCM 3724,F. necrophorum subspecies necrophorum (Fnn) and funduliforme (Fnf), respectively, and strain ARU 01 (Fnf), isolated from a patient with LS, were …
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Study of virulence factors of Staphylococcus aureus
… host. Both methods have been used to identify virulence genes in S. aureus. The main aim of this project was to find any probable new genes of S. aureus that are essential for biofilm formation and infection mouse model by STM. A library of tagged insertion mutants of S. aureus and a series of …
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Interplay Between Tryptophan Metabolites and the Virulence Factors of Enteric Pathogens
… a way that is conducive for its colonization and virulence gene expression. The role of these highly abundant tryptophan-derived small molecules in dictating the infectivity of an enteric pathogen remains unknown. Because the concentrations of these small molecules naturally present in the body …
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Staphylococcus aureus virulence factors dictate host signaling pathways and immune responses
… infections. This versatile pathogen expresses virulence factors (VF) that enhance establishment of infection and immune evasion. Our research focused on defining the roles of S. aureus VF on host immune responses during intracellular or extracellular infections. Accessory gene regulator (agr) …
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An Investigation of Histophilus somni Virulence Factors in Pathogenesis and Diagnosis
… whether luxS regulates the expression of various virulence genes, mRNA from both the parent strain and 2336::TnluxS was sequenced. It was determined that the transcription level of 53 genes in 2336::TnluxS and 42 genes in 2336::TnuspE in planktonic form were changed. In biofilm, 320 genes in …
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Comparison of Escherichia coli virulence factors with colony morphology on various media
Call number: LD2668 .T4 1979 A278
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Comparison of Escherichia coli virulence factors with colony morphology on various media
Call number: LD2668 .T4 1979 A278
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Studies on Virulence Factors of Clostridium perfringens and Necrotic Enteritis in Chickens
… overall AT results show that there must be other factors involved in the pathogenesis of necrotic enteritis. The protein profiles of two <em>netB </em>positive isolates with differing pathogenicity were used to determine potential virulence factors. The proteomic study revealed several potential …
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Knockout of the trans-acting riboswitches in Listeria monocytogenes to disrupt downstream virulence factors
… of this study is to reduce the downstream virulence factors that heavily rely on upregulation of the prfA gene. In this paper the pIMC plasmid is used in an attempt to knock-out the untranslated region (UTR) of the prfA gene located on the LIPI-1 pathogenicity island of the L. …
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Clostridium difficile: expression of virulence factors, resistance to disinfectants and interactions with human cells
… and decline of different strains of varying virulence and a broad spectrum of disease from asymptomatic carriage and mild infection to severe pseudomembranous colitis have been observed. The main aim of this three-part thesis was to identify bacterial factors that might explain these …
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Investigation of Haemophilus somnus Virulence Factors: Lipooligosaccharide Sialylation and Inhibition of Superoxide Anion Production
… diseases in cattle. One of the reported virulence factors that H. somnus may use to persist in the host is resistance to intracellular killing. It is reported in this dissertation that H. somnus significantly (P <0.001) inhibited production of superoxide anion (O2-) by bovine mammary and …
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Novel Virulence Factors in the Pathogenesis of Yersinia pestis Infection, the Causative Agent of Plague
Identification of new virulence factors in Yersinia pestis, the causative agent of plague, and understanding their molecular mechanisms during an infection process are necessary in designing a better vaccine or to formulate an appropriate therapeutic intervention. By using a high-throughput, …
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Structural and functional studies of type three secretion virulence factors from gram-negative pathogenic bacteria
… Despite their importance in promoting Shigella virulence, few molecular level details are known regarding the interactions between IpgC and its targets, IpaB and IpaC. Additionally, the mechanism by which DOC serves to stabilize a conformational change within IpaD is poorly understood. Methods …
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"Molecular Analysis of Virulence Factors Unique to Leptopilina heterotoma-a Parasitic Wasp of Drosophila spp."
… were identified. To understand how 9A08 exerts virulence, an unbiased and comprehensive Synthetic Genetic Array (SGA) screen covering all yeast genes was done to identify the cellular pathways or genetic networks most affected by 9A08 overexpression. While several potential categories of …
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The Effect of Environment on Virulence Factors and Resistance of Mucoid Strains of Pseudomonas Aeruginosa
… Both showed differences in the production of the virulence factors, protease, elastase, lipase, phospholipase C and pyocyanine and fluorescent pigments under different nutrient limitations. Growth conditions also affected exopolysaccharide production by M7. In general, phosphate and iron …
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The effect of subinhibitory concentrations of antibiotics on virulence factors of <i>Staphylococcus aureus</i> biofilms
… from humans. <i>S. aureus</i> produces numerous virulence factors that are responsible for the pathogenicity of this microorganism. Exposure of bacteria to sub-MICs of antibiotics is often encountered clinically, therefore, the effect of sub-MICs on staphylococcal virulence has been well studied …
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SPECIFIC RESIDUES WITHIN PSEUDOMONAS AERUGINOSA AmrZ ARE REQUIRED FOR TRANSCRIPTIONAL REGULATION OF VIRULENCE FACTORS CONTRIBUTING TO INFECTION
… in the immunocompromised. P. aeruginosa’s virulence factors include motility, adhesins, exotoxins, quorum sensing, biofilm and alginate production. Arguably, its ability to regulate expression of virulence factors and being able to switch to different infectious modes provides a strong …
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